Francesca R.
- Country
- Italy
- Department
- Gastroenterologia
Research Overview
- Phase 3 Randomized Double-Blind Placebo-Controlled Study of Tulisokibart Efficacy and Safety in Moderately to Severely Active Crohn's Disease
- Efficacy and Safety Evaluation of AZD7798 in Moderate to Severe Crohn's Disease: A Double-Blind, Placebo-Controlled Phase IIa Clinical Trial
- Open-Label Extension Study Assessing Long-Term Safety of Etrasimod Arginine in Patients with Moderately to Severely Active Ulcerative Colitis
Data & Insights
Has run more than one trial at 214 of 346 partner sites.
Specializations
Gastroenterology and Inflammatory Bowel Disease
The investigator is involved in clinical research on Crohn’s disease and ulcerative colitis, with additional interest in eosinophilic esophagitis, eosinophilic granulomatosis with polyangiitis, and intestinal inflammation. This area also includes studies related to abdominal pain, postoperative recurrence, and gastrointestinal immune-mediated disease.
- Crohn’s disease
- Ulcerative colitis
- Inflammatory bowel disease
- Eosinophilic esophagitis
Research activity in this field is centered at Azienda Ospedaliero Universitaria Careggi in Florence, reflecting a strong therapeutic focus on chronic digestive and immune-mediated disorders.
Thoracic Oncology
The investigator’s oncology portfolio includes extensive work in non-small cell lung cancer, small cell lung cancer, head and neck squamous cell carcinoma, and other thoracic malignancies. The clinical landscape also covers lung cancer with EGFR alterations, ALK-positive disease, and metastatic pulmonary tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- Head and neck squamous cell carcinoma
- Metastatic lung cancer
This research domain includes interest in targeted therapy, immunotherapy, and treatment strategies for advanced solid tumors.
Breast, Gynecologic, and Genitourinary Oncology
Clinical activity extends to breast cancer, including hormone receptor-positive and HER2-negative disease, triple-negative breast cancer, ovarian cancer, endometrial cancer, cervical cancer, prostate cancer, bladder cancer, and renal cell carcinoma. The therapeutic scope also includes urothelial carcinoma and gastroesophageal malignancies.
- Breast cancer
- Ovarian cancer
- Prostate cancer
- Renal cell carcinoma
Research interests in this section emphasize precision oncology, maintenance treatment, and management of metastatic disease.
Hematology and Blood Disorders
The investigator is active in studies of acute myeloid leukemia, chronic lymphocytic leukemia, myelodysplastic syndromes, multiple myeloma, lymphoma, and myeloproliferative neoplasms. Additional interests include hemophilia, immune thrombocytopenia, paroxysmal nocturnal hemoglobinuria, and thalassemia.
- Acute myeloid leukemia
- Myelodysplastic syndromes
- Multiple myeloma
- Hemophilia
This therapeutic area also includes bone marrow failure syndromes and other hematologic malignancies, with attention to supportive care and disease control.
Cardiovascular, Renal, and Immune-Mediated Diseases
Research involvement also covers atherosclerotic cardiovascular disease, atrial fibrillation, myocardial infarction, transthyretin amyloid cardiomyopathy, chronic kidney disease, IgA nephropathy, and lupus nephritis. The investigator is additionally engaged in studies of asthma, systemic sclerosis, rheumatoid arthritis, and multiple sclerosis.
- Atrial fibrillation
- Chronic kidney disease
- IgA nephropathy
- Transthyretin amyloid cardiomyopathy
The therapeutic profile includes cardiometabolic risk, renal protection, and autoimmune disease management across chronic multisystem conditions.
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