Florine T.
- Country
- France
- Department
- radiothérapie
Research Overview
Data & Insights
Has run more than one trial at 2 of 46 partner sites.
Specializations
Radiotherapy in central nervous system tumors
Clinical research activity includes brainstem gliomas, diffuse midline gliomas, and glioblastoma, with interest in radiation-based approaches for aggressive intracranial disease.
- Diffuse intrinsic pontine glioma
- Adult brain stem glioma
- Newly diagnosed glioblastoma
Therapeutic focus also extends to combining radiotherapy with systemic or device-based strategies in difficult-to-treat neuro-oncology settings.
Head and neck cancer and thoracic malignancies
The investigator is involved in studies addressing non-small cell lung cancer, small cell lung cancer, and squamous cell carcinoma of the head and neck, reflecting a strong interest in locally advanced and metastatic disease management.
- Non-small cell lung cancer
- Head and neck squamous cell carcinoma
- Unresectable stage III lung cancer
Research activity also includes chemoradiotherapy and immunotherapy-based treatment strategies in these tumor types.
Breast cancer and gynecologic oncology
Clinical trial involvement covers breast cancer, endometrial cancer, cervical cancer, ovarian cancer, and uterine leiomyosarcoma, with attention to both early-stage and advanced disease.
- HER2-positive metastatic breast cancer
- Advanced or recurrent endometrial cancer
- Ovarian cancer
Therapeutic interests include endocrine therapy, antibody-based treatment, and perioperative or adjuvant approaches in gynecologic malignancies.
Genitourinary cancers and molecularly selected solid tumors
Research activity includes prostate cancer, bladder cancer, renal cell carcinoma, and biomarker-defined solid tumors, with emphasis on advanced and metastatic disease.
- Metastatic castration-resistant prostate cancer
- Urinary bladder neoplasms
- Renal cell carcinoma
There is also involvement in targeted therapy and precision oncology for tumors with actionable genomic alterations.
Digestive system cancers and supportive oncology
The investigator contributes to studies in biliary tract cancer, gastroesophageal adenocarcinoma, colorectal cancer, and hepatocellular carcinoma, alongside supportive care research.
- Biliary tract carcinoma
- Gastroesophageal adenocarcinoma
- Chemotherapy-induced peripheral neuropathy
Therapeutic interests include adjuvant treatment, perioperative strategies, and symptom-focused management in oncology.
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