Florentino V.
- Country
- Spain
- Department
- Nephrology
Research Overview
- Efficacy and Safety of Intravenous Ravulizumab in Reducing Delayed Graft Function in High-Risk Adult Kidney Transplant Recipients: A Phase 3 Randomized Study
- Evaluation of Reduced Immunosuppression Regimen with Tacrolimus, Prednisolone, and Mycophenolate Sodium in Older Adult Kidney Transplant Recipients with End-Stage Renal Disease
Data & Insights
Has run more than one trial at 9 of 39 partner sites.
Specializations
Nefrology and Renal Transplantation
Clinical activity is centered on chronic renal disease, end-stage renal disease, and kidney-transplant care, with interest in preserving graft function and managing post-transplant complications.
- Delayed graft function after kidney transplantation
- Low-risk renal transplant patients
- Chronic renal disease
- End-stage renal disease
Therapeutic focus also includes renal-protective strategies in patients with moderate chronic kidney disease and prevention of kidney-related progression alongside cardiovascular risk reduction.
Bladder Cancer and Urothelial Malignancies
Research involvement extends across the spectrum of non-muscle-invasive bladder cancer, muscle-invasive urothelial carcinoma, and upper tract urothelial cancer, with attention to recurrence control and bladder preservation.
- High-risk non-muscle-invasive bladder cancer
- Muscle-invasive urothelial carcinoma
- Low-grade upper tract urothelial cancer
- Non-muscle-invasive urothelial carcinoma
Therapeutic interests include intravesical and systemic approaches for high-risk disease and strategies aimed at improving event-free survival and complete response in urothelial cancer.
Multiple Sclerosis and Neuroimmunology
The investigator is active in multiple sclerosis care, including relapsing multiple sclerosis, primary progressive multiple sclerosis, and fatigue-related symptom management.
- Relapsing multiple sclerosis
- Primary progressive multiple sclerosis
- Progressive multiple sclerosis
- Fatigue in multiple sclerosis
Additional therapeutic interest includes disease-modifying immunotherapy and supportive treatment for persistent neurological symptoms.
Hidradenitis Suppurativa and Inflammatory Skin Disease
Clinical trial activity includes hidradenitis suppurativa and related inflammatory dermatoses, with a focus on symptom control and long-term disease suppression.
- Hidradenitis suppurativa
- Chronic spontaneous urticaria
- Atopic dermatitis
- Non-segmental vitiligo
Therapeutic interests also cover chronic pruritic and autoimmune skin disorders where biologic and targeted anti-inflammatory treatments are being evaluated.
Cardiovascular, Hepatic, and Infectious Disease Care
Research involvement spans cardiovascular complications, liver cancer, acute infection management, and critical illness, reflecting a broad interest in complex internal medicine.
- Spontaneous coronary artery dissection
- Severe symptomatic aortic stenosis
- Intermediate-stage hepatocellular carcinoma
- Septic shock
Additional areas include acute pancreatitis, P. aeruginosa bacteremia, and suspected or confirmed Gram-negative infections, with attention to therapies that address organ protection and infection control.
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