Flore T.
- Country
- France
- Department
- Chirurgie viscérale
Research Overview
Data & Insights
Has run more than one trial at 8 of 28 partner sites.
Specializations
HIV Antiretroviral Therapy
Clinical research in HIV-1 infection includes treatment switching, first-line antiretroviral strategies, and maintenance approaches for virologically controlled patients, with attention to simplified regimens and resistance-associated mutations such as M184V/I.
- Antiretroviral regimen switch strategies
- Virological suppression maintenance
- HIV-HBV co-infection control
Additional work extends to long-acting and dual-therapy approaches in people living with HIV, reflecting a strong interest in optimizing durable viral control.
Osteoarticular Infection and Prosthetic Joint Infection
The investigator is active in the management of prosthetic joint infections, including infections due to Staphylococcus aureus, Cutibacterium spp., and mixed staphylococcal disease, with a focus on antibiotic strategies and adjunctive local or biological therapies.
- DAIR-based treatment pathways
- Staphylococcal prosthesis-related infection
- Phage-based adjunctive therapy
Research also covers related diabetic foot infections and device-associated bone and joint infection care.
Cardiovascular Disease and Thromboembolic Prevention
Clinical interests include prevention of stroke and systemic embolism in atrial fibrillation, as well as broader work in atherosclerotic cardiovascular disease and major adverse cardiovascular event reduction.
- Atrial fibrillation anticoagulation strategies
- ASCVD prevention
- Lipoprotein(a)-related cardiovascular risk
Research activity also includes therapies for heart failure with preserved or mildly reduced ejection fraction and obesity-associated cardiovascular risk.
Sepsis, Critical Care, and Acute Infection
The investigator is involved in studies addressing septic shock, acute infectious deterioration, and hospital-based respiratory infections, with interest in improving outcomes in critically ill adults.
- Septic shock management
- Acute respiratory infection treatment
- COVID-19 and viral infection care
Additional areas include uncomplicated candidemia, staphylococcal endocarditis, and infection-related kidney complications during critical illness.
Digestive Disease and Perioperative Care
Research interests also include Crohn’s disease, ulcerative colitis, and perioperative strategies in abdominal surgery, particularly in patients undergoing procedures for digestive cancer or hernia repair.
- Inflammatory bowel disease treatment optimization
- Digestive cancer surgery support
- Incisional hernia repair
Work in this domain further covers postoperative infection prevention and adjunctive approaches to surgical recovery.
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