Felicitas B.
- Country
- Germany
- Department
- Neurology
Research Overview
- The ENACT Trial: A Randomized, double-blind, placebo-controlled adjunctive treatment trial to evaluate the efficacy and safety of ENX-101 in patients with focal (partial onset) seizures
- Comparative Effectiveness of Levetiracetam and Valproate Semisodium in Benzodiazepine-Resistant Status Epilepticus in Patients Aged 65 and Older
- Evaluation of BHV-7000 as Adjunctive Therapy in Idiopathic Generalized Epilepsy with Generalized Tonic-clonic Seizures: A Randomized, Double-blind, Placebo-controlled Study
Data & Insights
Has run more than one trial at 89 of 162 partner sites.
Specializations
Hematologic Malignancies
Clinical research activity includes a strong focus on acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, and a broad spectrum of B-cell lymphomas, including chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma.
- Leukemia
- Lymphoma
- Myeloproliferative neoplasms
- Multiple myeloma
Therapeutic interest also extends to allogeneic hematopoietic cell transplantation, CAR T-cell therapy, and treatment strategies for relapsed or refractory blood cancers.
Breast Cancer and Other Solid Tumors
The investigator is involved in studies across breast cancer subtypes, including HER2-positive, hormone receptor-positive, and triple-negative breast cancer, as well as early breast cancer and metastatic disease. Additional work covers lung cancer, head and neck squamous cell carcinoma, ovarian cancer, pancreatic cancer, colorectal cancer, and urothelial carcinoma.
- Breast neoplasms
- Non-small cell lung cancer
- Head and neck cancer
- Gastrointestinal and hepatobiliary cancers
Therapeutic emphasis includes immunotherapy, targeted therapy, and perioperative treatment in advanced and locally advanced malignancies.
Neurology and Neurodegenerative Disease
Research involvement spans multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and frontotemporal dementia, with additional interest in progressive supranuclear palsy and other neurodegenerative diseases.
- Demyelinating disease
- Motor neuron disease
- Cognitive disorders
- Seizure disorders
Therapeutic domains also include neuroprotection and disease-modifying approaches for chronic neurological disorders.
Autoimmune, Inflammatory, and Transplant-Related Disorders
Clinical trial activity includes Crohn's disease, ulcerative colitis, systemic lupus erythematosus, rheumatoid arthritis, idiopathic inflammatory myopathies, Sjögren’s disease, and systemic sclerosis, together with graft-versus-host disease and other immune-mediated complications.
- Inflammatory bowel disease
- Systemic autoimmune disease
- Transplant immunology
- Immune-mediated neuromuscular disease
Therapeutic focus includes immune modulation and targeted intervention in refractory inflammatory conditions.
Pediatric, Rare, and Vision-Related Conditions
Additional research areas cover pediatric oncology such as neuroblastoma, medulloblastoma, and epithelial tumors in children, along with rare disorders including hereditary angioedema, beta-thalassemia, lipodystrophy, and myelofibrosis. Ophthalmic work includes age-related macular degeneration, central retinal vein occlusion, and myopia control.
- Pediatric rare diseases
- Inherited hematologic disorders
- Retinal disease
- Growth and metabolic disorders
Therapeutic interests include supportive and disease-modifying care for uncommon conditions across pediatric, hematologic, and ophthalmologic medicine.
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