Felice G.
- Country
- Italy
- Department
- Reparto di Cardiologia a Direzione Universitaria - Università della Campania “Luigi Vanvitelli”
Research Overview
Data & Insights
Has run more than one trial at 0 of 2 partner sites.
Specializations
Cardiovascular Disease & Acute Coronary Syndromes
The investigator concentrates on myocardial infarction, including ST‑elevation myocardial infarction, and the management of patients after successful percutaneous coronary intervention.
- acute myocardial infarction
- ST‑elevation myocardial infarction
- post‑PCI management
Efforts aim to lower the incidence of major adverse cardiac events in high‑risk coronary patients.
Atrial Fibrillation & Thromboembolic Prevention
Research addresses atrial fibrillation and strategies to prevent stroke and systemic embolism, especially in individuals unsuitable for conventional oral anticoagulation.
- atrial fibrillation
- stroke and systemic embolism
- anticoagulation alternatives
The focus is on safe and effective thromboprophylaxis within this arrhythmic population.
Dyslipidemia & Lipoprotein(a) Therapeutics
Key interests include treatment of elevated lipoprotein(a) and intensive LDL‑C lowering to mitigate atherosclerotic risk.
- lipoprotein(a) reduction
- inclisiran therapy
- pelacarsen studies
These approaches target patients with high‑risk atherosclerotic cardiovascular disease.
Oncology – Hormone‑Responsive Breast Cancer & Colorectal Cancer
The investigator’s oncology portfolio spans hormone receptor‑positive HER2‑negative breast cancer and RAS‑mutant metastatic colorectal cancer, integrating targeted and endocrine therapies.
- HR‑positive HER2‑negative breast cancer
- PIK3CA‑mutated breast cancer
- RAS‑wild‑type metastatic colorectal cancer
Clinical work explores novel combinations to improve progression‑free survival.
Inflammatory & Autoimmune Cardiovascular Research
Focused on the role of systemic inflammation in cardiovascular pathology, including trials of interleukin‑6 inhibition and assessments in systemic lupus erythematosus.
- IL‑6 pathway modulation
- ziltivekimab trials
- SLE responder index
The work links anti‑inflammatory therapy to reduced cardiovascular event rates.
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