Federica G.
- Country
- Italy
- Department
- Oncohematology
Research Overview
- Efficacy and Safety Evaluation of Selinexor and Ruxolitinib in Treatment-Naïve Myelofibrosis Patients: A Phase 1/3 Clinical Trial
- Phase 2 Multicentric Study of Venetoclax and Azacitidine in Adult NPM1-Mutated Acute Myeloid Leukemia with Molecular Relapse/Progression
- Efficacy and Safety Evaluation of Selinexor Monotherapy in JAK Inhibitor-Naïve Myelofibrosis Patients with Moderate Thrombocytopenia
Data & Insights
Has run more than one trial at 82 of 189 partner sites.
Specializations
Hematologic Malignancies
The investigator specializes in treating various forms of acute leukemia, with particular expertise in NPM1-mutated Acute Myeloid Leukemia and B-cell Lymphoblastic Leukemia. Their research encompasses innovative therapeutic approaches using targeted drug combinations.
- NPM1-mutated AML management
- Minimal residual disease in ALL
- Pre-transplant therapeutic strategies
A key focus lies in developing treatment protocols for patients preparing for hematopoietic stem cell transplantation.
Myeloproliferative Disorders
The investigator has extensive experience in treating myelofibrosis, including both primary and secondary forms. Their expertise extends to managing various subtypes of myeloproliferative disorders.
- Primary Myelofibrosis
- Post-PV/ET Myelofibrosis
- JAK inhibitor-naïve cases
Special attention is given to patients with moderate thrombocytopenia and various manifestations of myelofibrosis.
Novel Therapeutic Approaches
The investigator explores innovative treatment combinations for hematologic conditions, focusing on targeted therapies and novel drug applications.
- Selective inhibitor therapies
- Combination treatment strategies
- Treatment-naïve patient protocols
Their work includes evaluating therapeutic responses through specific markers like spleen volume reduction and symptom score improvements.
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