Evelyne M.
- Country
- Belgium
- Department
- Infectiologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 8 partner sites.
Specializations
Pediatric Hematologic Malignancies
The investigator concentrates on malignant blood disorders affecting children, including both lymphoid and myeloid lineages.
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Chronic Graft‑Versus‑Host Disease
- Lymphoblastic Lymphoma
- Acute Lymphoblastic Leukemia (Pediatric 0‑18 years)
These efforts aim to improve survival and reduce treatment‑related toxicity in young patients.
Pediatric Infectious Diseases & Transplant Complications
Focus is placed on viral, bacterial, and opportunistic infections that occur in immunocompromised children, especially after hematopoietic stem cell or solid organ transplantation.
- CMV infection in transplant recipients
- EBV‑positive post‑transplant lymphoproliferative disease
- Chronic hepatitis B infection
- Chronic hepatitis D virus infection
- Urinary tract infection with systemic involvement
Research addresses prevention, early detection, and tailored therapeutic strategies for these high‑risk infections.
Gastrointestinal & Hepatic Disorders in Children
Investigations target inflammatory bowel disease, liver dysfunction, and metabolic liver conditions in the pediatric population.
- Moderately to severely active Crohn's disease
- Ulcerative colitis
- Non‑Alcoholic Steatohepatitis (NASH)
- Metabolic Dysfunction‑Associated Steatotic Liver Disease (MASH)
- Hepatic encephalopathy
Therapeutic goals include inducing remission, preserving liver function, and preventing disease progression.
Cardiovascular & Metabolic Conditions
Research encompasses atherosclerotic disease, arrhythmias, and obesity‑related metabolic disturbances in both children and adults.
- Atherosclerotic Cardiovascular Disease (ASCVD)
- Atrial fibrillation
- Elevated Lp(a)
- Obesity
- Proteinuria
Efforts aim to identify novel therapeutic targets to reduce cardiovascular events and metabolic complications.
Neurological & Rare Genetic Disorders
The investigator addresses severe neurodevelopmental and neuromuscular diseases, as well as rare pediatric tumors.
- Dravet and Lennox‑Gastaut Syndromes
- Duchenne Muscular Dystrophy
- Spinal Muscular Atrophy (SMA)
- Atypical teratoid/rhabdoid tumours (ATRT)
- Medulloblastoma
Studies focus on disease‑modifying interventions and long‑term safety in these vulnerable groups.
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