Erion D.
- Country
- France
- Department
- Oncology
Research Overview
- Evaluation of Ribociclib Combined with Endocrine Therapy in Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: A Phase III Randomized Trial
- Phase III Randomized Study Comparing Chemotherapy Versus Endocrine Therapy with Abemaciclib in ER+ HER2- Breast Cancer with Visceral Metastases
- Phase III Non-Inferiority Trial of Ribociclib and Endocrine Therapy Versus Chemotherapy Plus Ribociclib in HR+ HER2- Intermediate-Risk Early Breast Cancer
Data & Insights
Has run more than one trial at 60 of 249 partner sites.
Specializations
Thoracic Oncology
Clinical research activity includes non-small cell lung cancer, small cell lung cancer, and other advanced thoracic malignancies, with interest in both locally advanced and metastatic disease and in post-operative treatment settings.
- Non-small cell lung cancer
- Small cell lung cancer
- Locally advanced thoracic cancer
- Resected lung cancer
Work in this area reflects involvement in modern immunotherapy and targeted therapy strategies for lung cancer care.
Breast and Gynecologic Oncology
The investigator is active in breast cancer, ovarian cancer, endometrial cancer, cervical cancer, and related gynecologic malignancies, including hormone receptor-defined and HER2-defined disease.
- Hormone receptor-positive breast cancer
- HER2-negative breast cancer
- Triple-negative breast cancer
- Ovarian and endometrial cancer
This portfolio also includes interest in PARP inhibitor-based approaches, antibody-based treatment, and biomarker-directed therapy in advanced solid tumors.
Gastrointestinal and Hepatobiliary Cancer
Research spans colorectal cancer, gastric cancer, pancreatic cancer, biliary tract cancer, and hepatocellular carcinoma, covering both resectable and unresectable disease.
- Metastatic colorectal cancer
- Gastric and gastroesophageal junction cancer
- Pancreatic adenocarcinoma
- Hepatocellular carcinoma
There is also involvement in gastrointestinal stromal tumor and neuroendocrine carcinoma research, with emphasis on treatment innovation in difficult-to-treat digestive cancers.
Hematologic Malignancies and Transplantation
Clinical interests include acute leukemia, lymphoma, myelodysplastic syndrome, multiple myeloma, and allogeneic stem cell transplantation in hematologic disease.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Post-transplant complications
Research activity also extends to graft-versus-host disease and supportive strategies around transplant-related care.
Inflammatory, Autoimmune, and Cardiovascular Disease
Beyond oncology, the investigator is involved in trials addressing inflammatory bowel disease, rheumatologic disease, autoimmune disorders, and selected cardiovascular disease settings.
- Crohn’s disease and ulcerative colitis
- Rheumatoid arthritis
- Lupus and vasculitis
- Myocardial infarction and stroke prevention
Additional interests include multiple sclerosis, asthma, and thromboembolic disease, showing engagement with broader therapeutic innovation across internal medicine.
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