Ephrem S.
- Country
- France
- Department
- Hepatobiliary and Transplantation Service
Research Overview
- Evaluation of Tacrolimus and Mycophenolate Mofetil in Immunosuppressive Regimens for Liver Transplant Recipients: A Comparative Study
- Evaluation of Lenvatinib Efficacy in Hepatocellular Carcinoma Patients on Liver Transplantation Waiting List Post-TACE Failure
- Evaluation of Atezolizumab and Bevacizumab Safety in Liver Transplant Recipients with Advanced Hepatocellular Carcinoma
Data & Insights
Has run more than one trial at 10 of 20 partner sites.
Specializations
Liver Cancer Research
The investigator specializes in treating advanced hepatocellular carcinoma (HCC), with particular focus on therapeutic approaches for patients with non-resectable conditions. Their research encompasses innovative treatment strategies for liver cancer patients awaiting transplantation.
- Advanced HCC Management
- Non-resectable Tumor Treatment
- Post-TACE Therapy
Their work includes evaluating lenvatinib treatment efficacy in patients who have experienced TACE failure.
Transplant Medicine
The investigator focuses on liver transplantation procedures and post-transplant care, with expertise in managing immunosuppressive therapies. Their work includes developing optimized treatment protocols for transplant recipients.
- Transplant Recipient Care
- Immunosuppressive Strategies
- Post-Transplant Monitoring
Their research involves studying single daily dose immunosuppressive regimens to improve patient outcomes after liver transplantation.
Immunotherapy Applications
The investigator studies combination immunotherapy approaches in transplant patients, particularly focusing on the application of atezolizumab and bevacizumab in liver transplant recipients with recurrent HCC.
- Transplant Immunology
- Cancer Immunotherapy
- Graft Rejection Prevention
Their research evaluates the safety of immunotherapy combinations while maintaining appropriate immunosuppression levels.
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