Enrique A. A.
- Country
- Spain
- Department
- Oncología
Research Overview
- Randomized, Double-Blind, Phase III Trial of Adjuvant Nivolumab Versus Placebo in Patients with Resected Esophageal or Gastroesophageal Junction Cancer
- Evaluation of Intensive Versus Standard Adjuvant Chemotherapy with FOLFOXIRI and CAPOX in Stage II-III Localized Colon Cancer with Circulating Tumor DNA
- Z0011001-A PHASE 1/2, OPEN-LABEL, MULTI-CENTER STUDY OF ZN-c3 ADMINISTERED IN COMBINATION WITH ENCORAFENIB AND CETUXIMAB IN ADULTS WITH METASTATIC COLORECTAL CANCER
Data & Insights
Has run more than one trial at 14 of 101 partner sites.
Specializations
Breast Cancer and Gynecologic Oncology
Clinical research in breast cancer includes hormone receptor-positive, HER2-negative, HER2-positive, and triple-negative breast cancer, with attention to early-stage, locally advanced, metastatic, and brain-metastatic disease. The gynecologic oncology portfolio covers ovarian cancer, endometrial cancer, cervical cancer, and related fallopian tube and primary peritoneal cancer.
- Breast cancer
- Ovarian cancer
- Endometrial cancer
- Cervical cancer
Therapeutic interests include endocrine therapy, targeted therapy, and immunotherapy across advanced and high-risk solid tumors.
Genitourinary and Renal Oncology
Research activity extends across urothelial carcinoma, bladder cancer, renal cell carcinoma, and prostate cancer, including metastatic and locally advanced disease. The landscape also includes high-risk non-muscle invasive bladder cancer and recurrent or treatment-resistant genitourinary malignancies.
- Urothelial carcinoma
- Bladder cancer
- Renal cell carcinoma
- Prostate cancer
Key therapeutic interests involve antibody-drug conjugates, immune checkpoint inhibition, and combination strategies for advanced genitourinary tumors.
Hematologic Malignancies
The investigator is involved in studies of multiple myeloma, lymphoma, chronic lymphocytic leukemia, and other blood cancers, including relapsed, refractory, and newly diagnosed settings. The portfolio also includes aggressive and indolent B-cell neoplasms and myelodysplastic conditions.
- Multiple myeloma
- Lymphoma
- Chronic lymphocytic leukemia
- Myelodysplastic syndromes
Therapeutic focus includes cell-based therapy, monoclonal antibodies, and novel regimens for disease control and relapse prevention.
Autoimmune, Inflammatory, and Dermatologic Diseases
Clinical interests include systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, systemic sclerosis, Crohn's disease, and ulcerative colitis. Skin-focused research also covers atopic dermatitis, hidradenitis suppurativa, psoriasis, prurigo nodularis, and vitiligo.
- Systemic lupus erythematosus
- Inflammatory bowel disease
- Atopic dermatitis
- Hidradenitis suppurativa
Therapeutic domains include biologic therapy, immune modulation, and treatment of chronic immune-mediated skin and joint disease.
Cardiometabolic, Renal, and Neurologic Disorders
The research landscape also includes atherosclerotic cardiovascular disease, heart failure, hypertension, dyslipidemia, obesity, type 2 diabetes, chronic kidney disease, IgA nephropathy, and focal segmental glomerulosclerosis. Neurologic interests include multiple sclerosis, Alzheimer's disease, myasthenia gravis, and migraine.
- Cardiovascular disease
- Chronic kidney disease
- Multiple sclerosis
- Alzheimer's disease
Therapeutic interests emphasize cardiovascular risk reduction, renal protection, and disease-modifying approaches in chronic metabolic and neurologic conditions.
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