Emmanouil S.
- Country
- Greece
- Department
- 300004: Hematology
Research Overview
- Phase 2, multicenter, open‑label study of extended‑dosing belantamab mafodotin in combination therapy for relapsed/refractory multiple myeloma
- Evaluation of Minimal Residual Disease Techniques in Untreated Multiple Myeloma with Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone Therapy
- Phase 3 Evaluation of Teclistamab with Lenalidomide versus Lenalidomide Monotherapy in Maintenance Therapy for Newly Diagnosed Multiple Myeloma Post-ASCT
Data & Insights
Has run more than one trial at 81 of 211 partner sites.
Specializations
Hematologic Malignancies
Acute myeloid leukemia, chronic lymphocytic leukemia, small lymphocytic lymphoma, diffuse large B-cell lymphoma, follicular lymphoma, marginal zone lymphoma, myelodysplastic syndromes, and multiple myeloma are central areas of clinical interest, with attention to both newly diagnosed and relapsed or refractory disease.
- Acute myeloid leukemia and myelodysplastic syndromes
- Multiple myeloma and plasma cell disorders
- B-cell lymphomas and chronic lymphocytic leukemia
Clinical work in this domain also includes maintenance therapy, transfusion-dependent anemia, and treatment strategies for high-risk or treatment-resistant blood cancers.
Cardiovascular and Thromboembolic Disease
Atrial fibrillation, acute myocardial infarction, acute coronary syndrome, heart failure, atherosclerotic cardiovascular disease, and stroke prevention form a major therapeutic focus, alongside cardiovascular risk reduction in complex comorbidity settings.
- Atrial fibrillation and rhythm control
- Stroke prevention and systemic embolism
- Heart failure and ischemic cardiovascular disease
Interest also extends to antithrombotic therapy, major adverse cardiovascular events, and protection against cardiorenal complications.
Respiratory and Pulmonary Disorders
Asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and nontuberculous mycobacterial lung infection are key respiratory areas, with additional involvement in severe and infection-related lung disease.
- Severe asthma and lung function decline
- Idiopathic pulmonary fibrosis
- Pulmonary arterial hypertension and chronic airway disease
Therapeutic activity in this field includes management of respiratory symptoms, airway inflammation, and progressive fibrotic lung disease.
Infectious Disease and Immune-Mediated Conditions
Sepsis, COVID-19, community-acquired pneumonia, complicated urinary tract infection, acute pyelonephritis, chronic hepatitis B, and chronic hepatitis C represent important infectious disease interests, with additional work in immune-driven inflammatory disorders.
- Sepsis and acute respiratory infections
- Viral hepatitis and post-viral syndromes
- Autoimmune inflammation and immune modulation
This research landscape also includes rheumatoid arthritis, ulcerative colitis, systemic sclerosis, and post-acute COVID syndrome.
Neurology, Ophthalmology, and Renal Disease
Acute ischemic stroke, transient ischemic attack, frontotemporal dementia, Alzheimer’s disease, refractory focal onset epilepsy, glaucoma, ocular hypertension, chronic kidney disease, and end-stage kidney disease define a broad cross-specialty interest in neurological, ocular, and renal therapeutic care.
- Stroke and neurovascular prevention
- Cognitive disorders and epilepsy
- Glaucoma and chronic kidney disease
Clinical involvement in these areas reflects attention to organ protection, functional preservation, and treatment of chronic complications affecting the nervous system, eye, and kidneys.
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