Elzbieta L. G.
- Country
- Poland
- Department
- Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego We Wroclawiu, Klinika Transplantacji S
Research Overview
- An open-label, parallel, Phase 3, two-arm study to investigate the efficacy and safety of fitusiran prophylaxis in male participants aged 1 to less than 12 years with hemophilia A or B with or without inhibitory antibodies to Factors VIII or IX
- Long-term safety and efficacy of denecimig prophylaxis in participants with haemophilia A with or without factor VIII inhibitors
Data & Insights
Has run more than one trial at 7 of 49 partner sites.
Specializations
Cardiovascular Medicine
The investigator is involved in clinical research across atrial fibrillation, heart failure, hypertension, and broader cardiovascular risk reduction, with attention to both structural and inflammatory heart disease.
- Heart failure with preserved or mildly reduced ejection fraction
- Worsening heart failure
- Transthyretin amyloidosis with cardiomyopathy
- Hypertension
Research activity also extends to left ventricular hypertrophy and cardiometabolic conditions linked to obesity and systemic inflammation.
Hematologic Malignancies
Clinical interests include treatment development for multiple myeloma, chronic lymphocytic leukemia, small lymphocytic lymphoma, and related relapsed or refractory blood cancers.
- Relapsed or refractory myeloma
- Chronic lymphocytic leukemia
- Small lymphocytic lymphoma
- Chronic myelogenous leukemia
The portfolio also includes Philadelphia chromosome-positive acute lymphoblastic leukemia and myelofibrosis, reflecting interest in advanced therapies for hematologic disease.
Autoimmune and Inflammatory Disease
The investigator participates in studies of systemic lupus erythematosus, Sjögren’s syndrome, and idiopathic inflammatory myopathies, with a focus on systemic immune-mediated disease.
- Systemic lupus erythematosus
- Primary Sjögren’s disease
- Polymyositis
- Dermatomyositis
Additional involvement includes systemic mastocytosis and other disorders characterized by persistent immune activation and multisystem involvement.
Metabolic, Infectious, and Preventive Care
Research activity also covers type 1 diabetes, preventive immunization, and infection-related disease prevention, alongside selected metabolic and cardiometabolic conditions.
- Type 1 diabetes mellitus
- Respiratory syncytial virus prevention
- Human papillomavirus prevention
- Obesity-associated heart failure
These interests include work on vaccination and prevention strategies relevant to pediatric and adult populations.
Ophthalmology and Urologic Oncology
The investigator is also connected to clinical research in glaucoma and urothelial cancer, broadening the therapeutic scope beyond systemic disease.
- Open-angle glaucoma
- Low-grade upper tract urothelial cancer
- Muscle invasive bladder cancer
- Upper tract urothelial carcinoma
This area reflects involvement in both vision-preserving therapy and oncologic treatment for genitourinary malignancies.
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