Elpis H.
- Country
- Greece
- Department
- Paediatric Pulmonology and C Unit - 3rd Paediatric Dept
Research Overview
- Study of BI 1015550 and nerandomilast to assess safety, dosing and efficacy in children and adolescents with fibrosing interstitial lung disease
- A Phase 3, Multicenter, Randomized, Partially Blinded, Palivizumab-Controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of MK-1654 in Infants and Children at Increased Risk for Severe RSV Disease
- Phase 2 Open-Label Study Evaluating Safety, Tolerability, and Efficacy of ARCT-032 (mRNA Encoding Human CFTR Gene) in Cystic Fibrosis Patients
Data & Insights
Has run more than one trial at 3 of 63 partner sites.
Specializations
Cystic Fibrosis Therapeutics
Focused on innovative treatments for Cystic Fibrosis in children and adolescents, addressing airway clearance and mucosal health.
- Cystic Fibrosis airway modulators
- CFTR protein correctors
- pulmonary infection management
Collaborates with the Ippokratio General Hospital’s paediatric unit to integrate clinical observations into therapeutic development.
Pediatric Hematologic Disorders
Specializes in hereditary blood conditions affecting young patients, including Alpha‑thalassemia and Sickle Cell Disease.
- Alpha‑thalassemia management strategies
- Sickle Cell Disease complication prevention
- transfusion‑dependent anemia therapies
Research aims to reduce transfusion burden and improve quality of life for paediatric hematology cohorts.
Pediatric Autoimmune and Inflammatory Skin Diseases
Investigates chronic dermatologic conditions such as Atopic Dermatitis, Hidradenitis Suppurativa, and severe plaque Psoriasis in children.
- Atopic Dermatitis immune modulation
- Hidradenitis Suppurativa lesion reduction
- Psoriasis skin clearance
Efforts emphasize safety and long‑term control of skin inflammation in the paediatric population.
Pediatric Oncology and Histiocytosis
Targets malignant and proliferative disorders including Acute Lymphoblastic Leukemia and Langerhans Cell Histiocytosis in children.
- Acute Lymphoblastic Leukemia treatment optimization
- Langerhans Cell Histiocytosis risk‑organ management
- relapse prevention strategies
Collaborative protocols aim to improve survival while minimizing late sequelae.
Pediatric Infectious Diseases
Addresses severe infections in children, focusing on Sepsis, Candidemia, and hospital‑acquired Pneumonia.
- Sepsis immunopathology
- Candidemia antifungal stewardship
- Pneumonia antimicrobial strategies
Research seeks to refine early intervention and reduce mortality in high‑risk paediatric cohorts.
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