Elli Sofia T.
- Country
- Greece
- Department
- Department of Medical Oncology
Research Overview
- Randomized Phase 3 Trial of Telisotuzumab adizutecan plus bevacizumab versus trifluridine/tipiracil plus bevacizumab in refractory metastatic colorectal cancer
- Evaluation of Safety and Efficacy of Telisotuzumab Adizutecan Combinations in Metastatic Colorectal Cancer: A Phase 2 Open-Label Randomized Study
Data & Insights
Has run more than one trial at 5 of 62 partner sites.
Specializations
Oncologic Therapeutics
The investigator’s work centers on targeted and immunologic strategies for a broad spectrum of solid tumors, including Non‑Small Cell Lung Cancer, Urothelial Carcinoma, Breast Cancer, Gastric and Gastroesophageal Junction Cancer, Colorectal Cancer, Prostate Cancer, Ovarian Cancer, and Endometrial Cancer.
- Non‑Small Cell Lung Cancer
- Urothelial Carcinoma
- Breast Cancer
- Gastric Cancer
- Colorectal Cancer
- Prostate Cancer
- Ovarian Cancer
- Endometrial Cancer
Efforts aim to improve survival outcomes across advanced disease stages.
Infectious Disease Management
Research includes immune modulation and antimicrobial approaches for severe infections such as Sepsis, Candidemia, and Hospital‑Acquired Bacterial Pneumonia caused by multidrug‑resistant organisms.
- Sepsis
- Candidemia
- Hospital‑Acquired Bacterial Pneumonia
Focus lies on reducing mortality and antimicrobial exposure.
Cardiovascular and Metabolic Health
Projects address cardiac dysfunction and risk, covering Heart Failure with Preserved Ejection Fraction, Heart Failure with Mildly Reduced Ejection Fraction, Hypertension, and broader High Cardiovascular Risk populations.
- Heart Failure with Preserved Ejection Fraction
- Heart Failure with Mildly Reduced Ejection Fraction
- Hypertension
- High Cardiovascular Risk
- Established Cardiovascular Disease
Therapeutic goals include lowering cardiovascular death and hospitalization.
Hepatology
The investigator explores disease‑modifying agents for cholestatic liver disease, notably Primary Biliary Cholangitis with cirrhosis.
- Primary Biliary Cholangitis
- Cirrhosis
Aim is to delay disease progression and improve liver function.
Neuropsychiatric Therapeutics
Studies target neuropsychiatric manifestations in neurodegenerative conditions, focusing on Psychosis Associated with Alzheimer’s Disease.
- Psychosis Associated with Alzheimer’s Disease
Research seeks to alleviate hallucinations and delusions while preserving cognition.
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