Elefteria H.
- Country
- Greece
- Department
- Department of Haematology
Research Overview
- A Randomized, Open-label, Phase 3 Study of Acalabrutinib in Combination with Rituximab and Reduced Dose CHOP (R-miniCHOP) in Older Adults with Untreated Diffuse Large B-Cell Lymphoma (ARCHED/GLA 2022-1)
- Evaluation of the Efficacy, Safety, and Tolerability of Subcutaneous REGN7999 in Adults with Iron Overload Due to Non-Transfusion Dependent Beta-Thalassemia
- Efficacy of Ziftomenib Combined with Standard of Care Therapy in Patients with Untreated NPM1-Mutated or KMT2A-Rearranged Acute Myeloid Leukemia
Data & Insights
Has run more than one trial at 323 of 549 partner sites.
Specializations
Haematologic Malignancies
The investigator is involved in clinical research across a broad spectrum of blood cancers, with activity in multiple myeloma, acute myeloid leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and aggressive lymphoma subtypes.
- Relapsed and refractory multiple myeloma
- Diffuse large B-cell lymphoma
- Mantle cell lymphoma
- Myelofibrosis
Research interests also extend to treatment-resistant disease, older adults with hematologic cancers, and therapies designed to improve control of marrow-related malignancies.
Cardiovascular and Thrombotic Disease
Clinical trial involvement includes prevention and treatment strategies for atherosclerotic cardiovascular disease, myocardial infarction, stroke, atrial fibrillation, and heart failure with reduced ejection fraction.
- Major adverse cardiovascular events
- Ischemic stroke prevention
- Venous thromboembolism
- Hypertension
Areas of interest also include lipid-related risk reduction, inflammation-linked cardiovascular disease, and interventions for patients with elevated lipoprotein(a).
Autoimmune, Inflammatory, and Renal Disorders
The investigator participates in studies of immune-mediated disease spanning idiopathic inflammatory myopathy, multiple sclerosis, Crohn’s disease, ulcerative colitis, and IgA nephropathy.
- Chronic kidney disease
- Proteinuria
- Primary Sjogren’s syndrome
- Immune thrombocytopenia
Therapeutic focus also includes secondary immunodeficiency, immune dysregulation, and inflammatory complications affecting renal function.
Respiratory and Pulmonary Medicine
Research activity covers chronic and progressive lung disease, including chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis.
- Bronchiectasis
- Severe asthma
- Post-acute COVID syndrome
- Respiratory exacerbations
The investigator also contributes to studies addressing lung function decline, pulmonary inflammation, and infection-related respiratory complications.
Metabolic, Endocrine, and Genetic Conditions
Additional clinical interests include type 2 diabetes, obesity, dyslipidaemia, familial hypercholesterolemia, and Fabry disease.
- Thalassemia
- Obesity-related cardiometabolic risk
- Elevated lipoprotein(a)
- Inherited metabolic disease
These activities reflect involvement in therapies targeting long-term metabolic risk, inherited blood disorders, and chronic organ complications.
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