Ekkehard S.
- Country
- Germany
- Department
- Kindergastroenterologie/Hepatologie
Research Overview
- Efficacy and Safety Evaluation of Odevixibat in Pediatric Biliary Atresia Post-Kasai Hepatoportoenterostomy: A Double-Blind, Randomized, Placebo-Controlled Trial
- An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia (BOLD-EXT)
- Efficacy and Safety of Obeticholic Acid in Pediatric Patients with Biliary Atresia Post-Hepatoportoenterostomy: A Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 18 of 25 partner sites.
Specializations
Pediatric Hepatology
This investigator specializes in treating rare pediatric liver disorders, with particular emphasis on Alagille Syndrome and Biliary Atresia. Their research focuses on innovative therapeutic approaches for children who have undergone Kasai hepatoportoenterostomy.
- Biliary Atresia Management
- Post-surgical Care
- Native Liver Survival
Their expertise extends to long-term treatment outcomes in pediatric liver conditions.
Rare Disease Therapeutics
The investigator's work centers on evaluating novel therapeutic agents for rare hepatic disorders, including odevixibat and obeticholic acid. Their research encompasses the assessment of treatments for managing chronic liver disease symptoms.
- Pruritus Management
- Portal Hypertension
- Hepatic Complications
The research encompasses both immediate and long-term therapeutic outcomes in pediatric populations.
Clinical Outcomes
This investigator focuses on evaluating comprehensive treatment outcomes in pediatric liver diseases, including end-stage liver disease prevention and management of portal hypertension complications.
- Disease Progression Markers
- Treatment Efficacy Assessment
- Long-term Safety Monitoring
Their research addresses critical aspects of pediatric liver disease management and treatment effectiveness.
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