Egon K.
- Country
- Slovakia
- Department
- #5506: Neurologická klinika
Research Overview
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Asundexian for Ischemic Stroke Prevention in Adults Post-Acute Non-Cardioembolic Stroke or High-Risk TIA
- Long-term Safety, Tolerability, and Efficacy Evaluation of Ofatumumab in Patients with Relapsing Multiple Sclerosis: An Open-label Extension Study
- A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention after an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack
Data & Insights
Has run more than one trial at 137 of 451 partner sites.
Specializations
Neurology and Neuroimmunology
Clinical research activity includes multiple sclerosis, relapsing multiple sclerosis, primary progressive multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathy, and chronic migraine, with additional interest in broader nervous system diseases.
- Multiple sclerosis
- Chronic inflammatory demyelinating polyneuropathy
- Multifocal motor neuropathy
The investigator is also involved in studies addressing ischemic stroke, high-risk transient ischemic attack, and stroke prevention in patients with cerebrovascular risk.
Autoimmune and Inflammatory Diseases
Therapeutic interests extend to atopic dermatitis, hidradenitis suppurativa, ulcerative colitis, eosinophilic esophagitis, and hereditary angioedema, reflecting a strong focus on immune-mediated and chronic inflammatory conditions.
- Atopic dermatitis
- Ulcerative colitis
- Hereditary angioedema
Research also includes immune globulin-related disorders and rare inflammatory syndromes affecting the gastrointestinal, dermatologic, and systemic domains.
Kidney and Complement-Mediated Disorders
Investigational work covers chronic kidney disease, IgA nephropathy, focal segmental glomerulosclerosis, Alport syndrome, and idiopathic immune complex mediated membranoproliferative glomerulonephritis, alongside complement-driven renal disease.
- Chronic kidney disease
- IgA nephropathy
- Focal segmental glomerulosclerosis
Additional interest includes atypical hemolytic uremic syndrome and proteinuria-focused renal research.
Cardiovascular and Thrombotic Risk
Clinical trial involvement includes acute coronary syndrome, anterior ST-elevation myocardial infarction, atherosclerotic cardiovascular disease, and prevention of major adverse cardiovascular events.
- Acute coronary syndrome
- Anterior ST-elevation myocardial infarction
- Atherosclerotic cardiovascular disease
Research also spans ischemic stroke prevention and thrombo-inflammatory conditions linked to vascular complications.
Hematology, Oncology, and Infectious Diseases
Additional therapeutic areas include hemophilia, fetal and neonatal alloimmune thrombocytopenia, primary immunodeficiency diseases, lymphoma, multiple myeloma, and prostate cancer, as well as infectious disease research in COVID-19, sepsis, and severe bacterial or viral lung infections.
- Hemophilia
- Lymphoma
- COVID-19
The portfolio also includes asthma, allergic rhinitis, and other respiratory-allergic conditions.
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