Efisio P.
- Country
- Italy
- Department
- Medicine and Surgery
Research Overview
- Long-Term Extension Study of Imeroprubart in Adult Patients With Graves' Disease
- Randomized Trial of Levothyroxine Sodium + Liothyronine Sodium versus Levothyroxine for TSH Control in Advanced Thyroid Carcinoma Patients on Tyrosine Kinase Inhibitors
- A Phase 2b Randomized Study of IMVT-1402 Versus Placebo in Adult Patients with Graves' Disease
Data & Insights
Has run more than one trial at 67 of 104 partner sites.
Specializations
Thoracic Oncology
Clinical research activity includes non-small cell lung cancer and small cell lung cancer, with interest in locally advanced, metastatic, resectable, and biomarker-selected disease. The portfolio also extends to ALK-positive, EGFR-mutant, and KRAS G12C-driven lung cancer, together with advanced solid tumors involving targeted and immune-based treatment strategies.
- Non-small cell lung cancer
- Small cell lung cancer
- ALK-positive lung cancer
- Metastatic solid tumors
Work at Hospital Santa Maria Della Misericordia in Perugia reflects a strong focus on precision oncology and treatment-resistant thoracic malignancies.
Haematologic Malignancies
The investigator is involved in trials spanning acute myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, and a broad range of B-cell lymphomas. Additional areas include follicular lymphoma, marginal zone lymphoma, mantle-related rare B-cell disorders, and relapsed or refractory lymphoid disease.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Chronic lymphocytic leukemia
- B-cell lymphomas
Research interest also covers cell therapy, bispecific antibodies, and targeted treatment for high-risk or relapsed hematologic cancers.
Melanoma and Other Solid Tumors
Clinical involvement includes melanoma across unresectable, metastatic, and resected settings, as well as uveal melanoma and cutaneous squamous cell carcinoma. The broader solid tumor portfolio includes breast cancer, ovarian cancer, prostate cancer, pancreatic cancer, and urothelial carcinoma.
- Melanoma
- Uveal melanoma
- Breast cancer
- Prostate cancer
These studies highlight interest in immunotherapy, adjuvant treatment, and advanced solid tumor management.
Cardiovascular and Thrombotic Disease
Research activity includes atrial fibrillation, ischemic stroke, acute coronary syndrome, heart failure with reduced ejection fraction, and atherosclerotic cardiovascular disease. The investigator also works in venous thromboembolism prevention and cardiovascular risk reduction.
- Atrial fibrillation
- Ischemic stroke
- Heart failure with reduced ejection fraction
- Atherosclerotic cardiovascular disease
Therapeutic interest extends to antithrombotic therapy, stroke prevention, and cardiometabolic risk.
Inflammatory, Autoimmune, and Neurologic Disorders
The investigator is also engaged in studies of atopic dermatitis, hidradenitis suppurativa, prurigo nodularis, polymyalgia rheumatica, systemic lupus erythematosus, rheumatoid arthritis, and Sjögren’s disease. Neurologic and metabolic interests include Alzheimer’s disease, migraine, multiple sclerosis, type 2 diabetes, and obesity.
- Atopic dermatitis
- Prurigo nodularis
- Polymyalgia rheumatica
- Alzheimer’s disease
Additional attention is given to ophthalmic disease, including neovascular age-related macular degeneration and open-angle glaucoma.
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