Edyta K.
- Country
- Poland
- Department
- NA
Research Overview
- An Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Donidalorsen in Pediatric Patients with Hereditary Angioedema
- Phase 3 Open‑Label Single‑Arm Study of Subcutaneous Zodasiran (ARO‑ANG3) in Adolescents With Homozygous Familial Hypercholesterolemia
- Efficacy and Safety of Infliximab, Tofacitinib, and Vedolizumab in Induction-Resistant Ulcerative Colitis: A Comparative Analysis
Data & Insights
Has run more than one trial at 7 of 157 partner sites.
Specializations
Inflammatory Bowel Disease
Clinical research activity is centered on ulcerative colitis and Crohn’s disease, including moderate to severe disease, pediatric disease, and treatment-resistant presentations. Interest also extends to pouchitis, perianal fistulizing disease, fibrostenotic Crohn’s disease, and broader inflammatory bowel diseases.
- Ulcerative colitis
- Crohn’s disease
- Complex perianal fistulas
- Active chronic pouchitis
- Fibrostenotic disease
Therapeutic focus includes advanced targeted therapies, biologic treatment, and long-term disease control in both adult and pediatric gastroenterology.
Pediatric Gastroenterology and Intestinal Disorders
The investigator is involved in trials addressing pediatric ulcerative colitis, pediatric Crohn’s disease, intestinal failure, and related gastrointestinal conditions. Additional interests include celiac disease, eosinophilic esophagitis, eosinophilic gastritis, and gastroesophageal reflux disease in children.
- Pediatric ulcerative colitis
- Pediatric Crohn’s disease
- Intestinal failure
- Celiac disease
- Eosinophilic gastrointestinal disease
Research activity also covers symptomatic nonerosive GERD, erosive esophagitis, and pediatric patients with complex digestive-system disorders.
Immune-Mediated and Allergic Disease
Clinical trial involvement includes atopic dermatitis, primary immunodeficiency diseases, hereditary angioedema, IgG4-related disease, and juvenile psoriatic arthritis. The portfolio also includes immune-driven conditions with gastrointestinal or systemic inflammatory features.
- Atopic dermatitis
- Primary immunodeficiency
- Hereditary angioedema
- IgG4-related disease
- Juvenile psoriatic arthritis
Therapeutic interest is directed toward immune modulation and anti-inflammatory treatment across chronic immune-mediated disorders.
Hepatology and Metabolic Liver Disease
Research activity includes metabolic dysfunction-associated steatotic liver disease, metabolic dysfunction-associated steatohepatitis, nonalcoholic steatohepatitis, and liver fibrosis. Additional areas include alpha-1 antitrypsin deficiency-associated liver disease, biliary atresia, Wilson’s disease, and chronic viral hepatitis B.
- MASH and MASLD
- Liver fibrosis
- Alpha-1 antitrypsin deficiency-associated liver disease
- Biliary atresia
- Wilson’s disease
The therapeutic landscape also includes cholestatic pruritus, alcoholic liver disease, and other chronic hepatobiliary disorders.
Neurology, Kidney, and Rare Disease Therapies
The investigator’s trial portfolio extends to multiple sclerosis, neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody-associated disease, epilepsy, and tuberous sclerosis complex. Additional involvement includes chronic kidney disease, proteinuria, spinal muscular atrophy, and selected rare metabolic diseases.
- Multiple sclerosis
- Neuromyelitis optica spectrum disorder
- Epilepsy and tuberous sclerosis complex
- Chronic kidney disease
- Spinal muscular atrophy
Research also spans pulmonary arterial hypertension, heart failure, and other complex multisystem conditions linked to innovative therapeutic development.
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