Edoardo L. P.
- Country
- Italy
- Department
- U.O. Nephrology
Research Overview
Data & Insights
Has run more than one trial at 0 of 27 partner sites.
Specializations
Pediatric Chronic Kidney Disease and Proteinuria
Investigates strategies to slow progression of chronic kidney disease in children, with an emphasis on controlling proteinuria and optimizing growth.
- Early biomarkers for renal decline
- Antiproteinuric therapies in paediatric CKD
- Nutrition and metabolic support for children with CKD
Targets long‑term renal preservation and quality of life in the pediatric population.
Glomerular Diseases
Focuses on primary glomerulopathies such as focal segmental glomerulosclerosis, minimal change disease, IgA nephropathy, and hereditary conditions like Alport syndrome.
- Genetic profiling of hereditary glomerular disorders
- Targeted immunomodulation for FSGS
- Risk stratification in IgA nephropathy
Seeks to personalize treatment based on disease mechanisms and patient genetics.
Renal Transplantation and Immunosuppression
Explores optimal immunosuppressive regimens and conversion strategies for paediatric kidney transplant recipients, including the use of belatacept and monitoring of calcineurin inhibitor toxicity.
- Belatacept‑based conversion protocols
- Therapeutic drug monitoring of tacrolimus
- Management of post‑transplant infections
Aims to improve graft survival while minimizing adverse effects.
Lupus Nephritis and Systemic Autoimmune Renal Involvement
Dedicated to the treatment of lupus nephritis and related renal manifestations of systemic autoimmune diseases, integrating biologic agents and precision dosing.
- Biologic therapy for refractory lupus nephritis
- Biomarker‑guided tapering of steroids
- Long‑term safety of anti‑CD20 agents in paediatric SLE
Strives to achieve durable remission with reduced steroid exposure.
Hemolytic Uremic Syndrome and Thrombotic Microangiopathy
Addresses acute and chronic management of hemolytic uremic syndrome and post‑transplant thrombotic microangiopathy, focusing on complement inhibition and supportive care.
- Eculizumab use in atypical HUS
- Plasma exchange protocols in pediatric TMA
- Renal recovery predictors after HUS episodes
Targets rapid disease control and preservation of renal function.
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