Dr. Yury Y.
- Country
- Germany
- Department
- HNO, Allergology
Research Overview
- Efficacy and Safety Evaluation of Subcutaneous Cluster-Immunotherapy with Allergen Extract from Phleum pratense Pollen in Moderate-to-Severe Grass Pollen Allergy
- Efficacy and Safety Evaluation of Phleum Pratense Pollen Extract Sublingual Immunotherapy in Moderate-to-Severe Grass Pollen-Induced Allergic Rhinitis Patients
- Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from house dust mite allergy. A prospective, international, randomized, double-blind, placebo-controlled, multicentre, phase II-III trial.
Data & Insights
Has run more than one trial at 3 of 6 partner sites.
Specializations
Allergic Rhinitis and Rhinoconjunctivitis
Dr. Yury Yarin’s clinical research centers on seasonal allergic rhinitis and rhinoconjunctivitis, with a strong focus on pollen-driven disease burden in birch pollen and grass pollen allergy, as well as perennial allergic rhinitis linked to house dust mite sensitization.
- Birch pollen-induced allergic rhinitis
- Grass pollen-induced allergic rhinitis
- House dust mite-associated allergic rhinitis
- Perennial allergic rhinitis
His work includes clinical interest in symptom control, nasal obstruction, and the broader impact of allergen exposure on upper-airway disease.
Allergen Immunotherapy
His trial activity is closely aligned with subcutaneous immunotherapy and sublingual immunotherapy for inhalant allergies, particularly in patients with clinically significant sensitivity to birch pollen, grass pollen, and house dust mites.
- Subcutaneous immunotherapy for birch pollen allergy
- Subcutaneous immunotherapy for grass pollen allergy
- Sublingual immunotherapy for birch pollen allergy
- Sublingual immunotherapy for grass pollen allergy
- Sublingual immunotherapy for house dust mite allergy
This area reflects a therapeutic emphasis on disease modification in IgE-mediated allergy affecting the upper respiratory tract.
House Dust Mite-Driven Airway Disease
Dr. Yarin is involved in studies addressing moderate-to-severe allergic rhinitis and rhinoconjunctivitis caused by house dust mite allergy, including cases with associated asthma.
- Moderate-to-severe HDM-induced allergic rhinitis
- Allergic rhinitis/rhinoconjunctivitis with asthma
- Persistent house dust mite sensitization
His therapeutic interest extends to long-standing, clinically burdensome perennial allergen exposure and its effect on nasal and respiratory symptoms.
Chronic Rhinosinusitis with Nasal Polyps
Another key area is chronic rhinosinusitis with nasal polyps (CRSwNP), with attention to nasal congestion, polyp burden, and symptom relief in patients with persistent inflammatory sinonasal disease.
- Chronic rhinosinusitis with nasal polyps
- Nasal congestion
- Nasal polyp disease
His research landscape also includes biologic treatment strategies for upper-airway inflammation in CRSwNP.
Biologic Therapy for Upper-Airway Inflammation
Dr. Yarin’s clinical trial portfolio includes interest in emerging biologic therapy for refractory allergic and sinonasal disease, particularly in settings where conventional symptom control remains insufficient.
- Anti-inflammatory biologics for rhinitis
- Biologic treatment for nasal polyps
- Targeted therapy for chronic sinonasal inflammation
This domain connects his work in allergology and otorhinolaryngology with therapeutic innovation in upper-airway disease.
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