Michaela K.
- Country
- Germany
- Department
- Clinic for Pediatrics and Adolescent Medicine
Research Overview
- Randomized Phase 3 Trial of Venetoclax Added to Fludarabine, High‑Dose Cytarabine, and Gemtuzumab Ozogamicin in Children with Relapsed Acute Myeloid Leukemia
- Evaluation of Metformin and Metformin Hydrochloride for Cancer Prevention in Adolescents and Adults with Li-Fraumeni Syndrome: A Phase IIIb Randomized Open-Label Trial
Data & Insights
Has run more than one trial at 1 of 30 partner sites.
Specializations
Pediatric Hematologic Malignancies
Focused investigation of blood cancers that primarily affect children and adolescents.
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Chronic Myeloid Leukemia
- Myelodysplastic Syndromes
- Hematopoietic Stem Cell Transplantation
Emphasis on transplant‑based strategies and targeted molecular approaches.
Solid Tumor Oncology
Broad engagement with adult solid malignancies across multiple organ systems.
- Non‑Small Cell Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Hepatocellular Carcinoma
- Prostate Cancer
Includes work on metastatic disease and high‑risk therapeutic scenarios.
Immunological and Allergic Disorders
Research addressing immune‑mediated and allergic conditions.
- Atopic Dermatitis
- Chronic Urticaria
- Crohn’s Disease
- Ulcerative Colitis
- Systemic Lupus Erythematosus
Focus on disease‑modifying biologic therapies.
Neurological and Neuro‑Oncologic Conditions
Investigation of central nervous system malignancies and related neurological diseases.
- Glioblastoma
- Medulloblastoma
- Diffuse Intrinsic Pontine Glioma
- H3 K27M‑mutant Diffuse Glioma
- Ewing Sarcoma
Targeted molecular therapies are a central component of the work.
Metabolic and Rare Diseases
Engagement with metabolic disorders and genetically defined rare conditions.
- Amyloidosis
- Type 1 Diabetes
- Li‑Fraumeni syndrome
- Idiopathic Gastroparesis
- Turner Syndrome
Precision‑medicine approaches guide therapeutic development.
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