Dominique G.
- Country
- France
- Department
- Medical Oncology
Research Overview
- Phase II Trial of Durvalumab, Olaparib, and Fulvestrant in ER-Positive, HER2-Negative Metastatic Breast Cancer with BRCA or HRR Gene Alterations
- Evaluation of Palbociclib Combined with Endocrine Therapy in ER+/HER2- Metastatic Breast Cancer Using Circulating DNA ESR1 Mutation Monitoring
- Evaluation of Reduced Duration of Adjuvant Endocrine Therapy with Exemestane, Anastrozole, and Letrozole in Postmenopausal Women with Low-Risk HR+ HER2- Breast Cancer
Data & Insights
Has run more than one trial at 142 of 359 partner sites.
Specializations
Breast Cancer Specialization
Focuses on advanced treatment approaches for hormone receptor-positive (HR+) and HER2-negative breast cancer, with particular emphasis on developing therapeutic strategies for metastatic conditions.
- Metastatic breast cancer management
- Hormone therapy optimization
- Treatment resistance mechanisms
Investigates novel therapeutic combinations including targeted therapies and endocrine treatments.
Precision Medicine Applications
Specializes in biomarker-driven treatment approaches and personalized therapy selection, particularly focusing on molecular profiling in breast cancer.
- Circulating tumor DNA analysis
- Genetic mutation tracking
- Treatment response monitoring
Explores innovative diagnostic methods to guide therapeutic decision-making.
Immunotherapy Research
Conducts studies on combination immunotherapy approaches in breast cancer treatment, including investigation of novel immune checkpoint inhibitors.
- Targeted therapy combinations
- Immune response monitoring
- Treatment sequencing strategies
Evaluates innovative immunotherapeutic approaches in various breast cancer subtypes.
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