Domenico S.
- Country
- Italy
- Department
- U.O.C. di Nefrologia e Dialisi
Research Overview
- Evaluation of Pegcetacoplan for Reducing Proteinuria in Adults and Adolescents with Focal Segmental Glomerulosclerosis
- A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Immunoglobulin A Nephropathy
- Evaluation of Corticosteroids, Dapagliflozin, and RASBs on Proteinuria in IgA Nephropathy Patients with Active and Chronic Renal Lesions
Data & Insights
Has run more than one trial at 73 of 315 partner sites.
Specializations
Nephrology Focus
The investigator specializes in treating IgA nephropathy (IgAN), conducting research on targeted therapeutic approaches and novel treatment strategies. Their work encompasses both early intervention protocols and chronic disease management for this specific kidney condition.
- Targeted therapy based on biopsy findings
- Early corticosteroid interventions
- Novel biological treatments
Additional expertise includes evaluation of innovative therapeutic agents like sibeprenlimab for IgAN treatment.
Chronic Kidney Disease Management
The investigator focuses on chronic kidney disease (CKD) progression and innovative therapeutic approaches. Their research extends to investigating various agents for slowing disease progression and managing complications.
- Disease progression markers
- Albumin reduction strategies
- Standard of care optimization
Particular attention is given to end-stage kidney disease (ESKD) and cardiovascular complications in dialysis patients.
Specialized Conditions
The investigator has expertise in treating Autosomal Dominant Polycystic Kidney Disease (ADPKD), exploring comparative therapeutic approaches and investigating alternative treatment options.
- Therapeutic equivalence studies
- Kidney function preservation
- Alternative medication evaluation
Research includes comparative studies of metformin and tolvaptan in ADPKD management.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.