Djamila I.
- Country
- The Netherlands
- Department
- Hematology
Research Overview
- HOVON 165 CLL: A prospective randomized phase I/II trial of venetoclax treatment (26 cycles) with 6 cycles or 12 cycles of epcoritamab in patients with relapsed or refractory chronic lymphocytic leukemia or Small Lymphocytic Lymphoma. AETHER study (ABT199 + Epcoritamab THErapy for Relapsed/refractory CLL/SLL)
- Phase 3 Randomized Study of Epcoritamab Plus R-CHOP Versus R-CHOP in Newly Diagnosed Diffuse Large B-Cell Lymphoma Patients
- Evaluation of BrECADD Versus Escalated BEACOPP in First-Line Treatment of Advanced Hodgkin Lymphoma: A Randomized Controlled Trial
Data & Insights
Has run more than one trial at 134 of 408 partner sites.
Specializations
Lymphoid Malignancies
The investigator specializes in treating various forms of lymphoid cancers, with particular focus on chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL). Their research encompasses both newly diagnosed cases and relapsed/refractory disease states.
- CLL without del(17p) or TP53 mutation
- Small Lymphocytic Lymphoma
- Advanced Stage Hodgkin Lymphoma
The investigator explores innovative therapeutic combinations including targeted agents and immunotherapy approaches.
Novel Therapeutic Approaches
Their research portfolio includes evaluation of cutting-edge treatments involving targeted therapies such as acalabrutinib and venetoclax, combined with established therapeutic options.
- Antibody-Based Therapies
- Targeted Molecular Agents
- Combination Treatment Strategies
The investigator's work incorporates both traditional chemotherapy and modern targeted approaches.
Treatment Optimization
The investigator focuses on developing optimized treatment protocols for aggressive lymphomas, including mantle cell lymphoma and comparative studies of various therapeutic regimens.
- First-line Treatment Protocols
- Maintenance Therapy Strategies
- Autologous Stem Cell Transplantation
Their research aims to establish improved standards of care through systematic evaluation of treatment combinations.
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