Dirk A.
- Country
- Germany
- Department
- Asklepios Klinik Altona Abteilung Onkologie, Hämatologie
Research Overview
- A Phase I/II Study of KISIMA-02 Vaccine-Based Immunotherapy in KRAS G12D/G12V Mutated Pancreatic Ductal Adenocarcinoma Patients
- Evaluation of Safety and Efficacy of Targeted Therapies in Metastatic Colorectal Cancer Subpopulations
- Evaluation of the Safety, Tolerability, and Efficacy of the Pan-KRAS Inhibitor LY4066434 in Patients with KRAS Mutant Advanced Solid Tumors
Data & Insights
Has run more than one trial at 354 of 630 partner sites.
Specializations
Gastrointestinal Oncology
The investigator specializes in treating various types of colorectal cancer, including advanced metastatic cases with specific genetic markers such as MSI-H/dMMR and HER2-positive variants. Their research extends to biliary tract cancer and pancreatic ductal adenocarcinoma.
- Metastatic Colorectal Cancer Treatment
- Pancreatic Cancer Therapeutics
- Biliary Tract Malignancies
Head and Neck Cancer
Focuses on advanced treatments for head and neck squamous cell carcinoma, particularly in recurrent and metastatic cases. The investigator works with novel therapeutic approaches including immunotherapy combinations and targeted treatments.
- Recurrent HNSCC Management
- Metastatic Disease Treatment
- Combined Therapy Approaches
Precision Medicine
Investigates personalized treatment approaches targeting specific genetic alterations including FGFR mutations, HER2 alterations, and NRG1 fusions across various solid tumors. Expertise in developing targeted therapies for molecular subtypes of cancer.
- Molecular-Targeted Therapies
- Biomarker-Driven Treatment
- Gene Alteration Studies
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