Diego K. G.
- Country
- Germany
- Department
- Medizinischen Klinik und Poliklinik V
Research Overview
- ETOP 23-22 RAISE: A single-arm phase II study of the addition of niraparib to anti-PD-L1 antibody maintenance in patients with SLFN11-positive, extensive-disease small cell lung cancer.
- Phase 3 Randomized Study of Nivolumab + Relatlimab FDC with Chemotherapy vs. Pembrolizumab with Chemotherapy in Stage IV/Recurrent NSCLC with PD-L1 ≥1%
- Phase 2 Study of BMS-986504 Monotherapy in Advanced/Metastatic NSCLC with Homozygous MTAP Deletion Post-Therapy Progression
Data & Insights
Has run more than one trial at 29 of 168 partner sites.
Specializations
Oncology and hematologic malignancies
Clinical research activity includes a broad range of solid tumors and blood cancers, with emphasis on advanced non-small cell lung cancer, breast cancer, gastrointestinal cancers, and rare malignant diseases such as lymphoma, leukemia, and multiple myeloma.
- Non-small cell lung cancer
- Breast cancer
- Lymphoma and leukemia
- Gastrointestinal and biliary tract cancers
- Multiple myeloma
Therapeutic interest extends to molecularly defined cancer subtypes, metastatic disease, and treatment-resistant malignancies, reflecting involvement in modern targeted therapy and immuno-oncology development.
Inflammatory, autoimmune, and rheumatologic diseases
Research involvement covers chronic immune-mediated disorders affecting the joints, skin, gut, and connective tissue, with attention to psoriatic arthritis, rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and systemic autoimmune conditions.
- Psoriatic arthritis
- Rheumatoid arthritis
- Crohn’s disease
- Ulcerative colitis
- Systemic lupus erythematosus and Sjögren’s disease
Additional therapeutic focus includes bullous pemphigoid, hidradenitis suppurativa, psoriasis, and related inflammatory syndromes requiring advanced immune modulation.
Pulmonary, cardiovascular, and critical care medicine
Investigational work spans chronic and acute respiratory disease, pulmonary vascular disorders, and cardiovascular complications, including asthma, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, heart failure, and acute coronary syndromes.
- Asthma and chronic obstructive pulmonary disease
- Interstitial lung disease and pulmonary fibrosis
- Pulmonary arterial hypertension
- Heart failure
- Acute ischemic stroke and acute coronary syndromes
Therapeutic interests also include sepsis, acute kidney injury, and transplant-related cardiopulmonary complications in medically complex patients.
Neurology and neurodegenerative disorders
Clinical trial activity includes a strong focus on disorders of cognition, movement, and excitability, with studies in Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, epilepsy, and migraine.
- Alzheimer’s disease and dementia
- Parkinson’s disease and progressive supranuclear palsy
- Multiple sclerosis
- Epilepsy
- Migraine and Tourette’s disorder
Research also includes myasthenia gravis, autoimmune encephalitis, and other neurologic conditions where disease modification and symptom control remain important therapeutic goals.
Kidney, transplant, and rare disease therapeutics
Additional clinical interest is centered on renal and transplant-related disorders, with studies in chronic kidney disease, IgA nephropathy, lupus nephritis, glomerulonephritis, and transplant rejection.
- Chronic kidney disease
- IgA nephropathy
- Lupus nephritis
- Transplant rejection
- Rare genetic and metabolic disorders
Therapeutic involvement further extends to amyloidosis, cystic fibrosis, and selected inherited or multisystem conditions requiring specialized long-term management.
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