DI MAIO M.
- Country
- France
- Department
- NEONATOLOGIE
Research Overview
- Phase III Randomized Trial of Preoperative Chemotherapy vs. Chemotherapy Plus Chemoradiotherapy in Locally Advanced Resectable Rectal Carcinoma
- Safety and Feasibility of Autologous Cord Blood-Derived Mononuclear Cells in Neonatal Hypoxic-Ischemic Encephalopathy
- Phase 3 Evaluation of Lenalidomide and Daratumumab SC Versus Lenalidomide and Dexamethasone in Frail, Newly Diagnosed Multiple Myeloma Patients Ineligible for High-Dose Therapy
Data & Insights
Has run more than one trial at 29 of 103 partner sites.
Specializations
Neonatal medicine and perinatal care
Clinical research interests include preterm infant nutrition, respiratory distress syndrome, intestinal malabsorption, and neonatal hypoxic-ischaemic encephalopathy, with attention to early-life support and outcomes in vulnerable newborns.
- Preterm birth and high-risk pregnancy
- Neonatal respiratory disorders
- Feeding and gastrointestinal adaptation
- Perinatal neurological injury
Work in this area aligns with care delivered at Centre Hospitalier Universitaire De Nimes and reflects a strong focus on infant health in the neonatal setting.
Paediatric and developmental neurology
The investigator is involved in studies addressing multiple sclerosis, progressive supranuclear palsy, Parkinson's disease, cerebral palsy, and other neurological disease presentations across childhood and adulthood.
- Multiple sclerosis and demyelinating disease
- Movement disorders
- Neurodevelopmental syndromes
- Neuropathic pain
Therapeutic interest also extends to symptom control in complex neurological disorders and functional impairment.
Cardiovascular disease and thromboembolic prevention
Research activity covers acute coronary syndrome, myocardial infarction, heart failure, atrial fibrillation, cardiogenic shock, and broader atherosclerotic cardiovascular disease.
- Acute and chronic coronary syndromes
- Heart failure and valvular heart disease
- Stroke prevention and anticoagulation
- Cardiac rhythm disorders
Interest also includes recovery after cardiac arrest and prevention of recurrent vascular events.
Renal disease and autoimmune nephrology
The investigator’s portfolio includes chronic kidney disease, acute kidney injury, end-stage renal disease, IgA nephropathy, membranous nephropathy, and ANCA-associated vasculitis.
- Glomerular disease
- Hypertension with renal involvement
- Renal vasculitis
- Proteinuric kidney disease
Therapeutic interest also includes renal protection in patients with diabetes mellitus and cardiorenal syndrome.
Infectious disease, critical care, and perioperative medicine
Clinical trial involvement spans septic shock, hospital-acquired pneumonia, urinary tract infection, prosthetic joint infection, COVID-19, and HIV infection, alongside perioperative prevention strategies.
- Severe bacterial infection
- Intensive care management
- Surgical infection prophylaxis
- Viral infection treatment
Research also includes general anesthesia, sedation, and infection-related complications in hospitalized patients.
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