Despoina T.
- Country
- Greece
- Department
- 4th Pediatric Clinic
Research Overview
- Evaluation of Long-term Safety and Tolerability of Human Normal Immunoglobulin and Hyaluronidase (Human Recombinant) in Primary Immunodeficiency Diseases
- Multicenter, Prospective, Open-label, Randomized, Crossover Study to Evaluate Pharmacokinetics (PK), Safety, and Tolerability of TAK-881 in Primary Immunodeficiency Diseases (PIDD)
- Evaluation of Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Pediatric Patients with Complicated Urinary Tract Infection, Including Acute Pyelonephritis
Data & Insights
Has run more than one trial at 15 of 47 partner sites.
Specializations
Pediatric Gastroenterology and Inflammatory Bowel Disease
Clinical research activity includes ulcerative colitis and other gastrointestinal inflammatory disorders, with interest in therapies aimed at controlling intestinal inflammation and maintaining remission in younger patients.
- Ulcerative colitis
- Pediatric inflammatory bowel disease
- Gastrointestinal inflammation
The therapeutic focus extends to chronic immune-mediated disease management within pediatric care.
Dermatology and Immune-Mediated Skin Disease
Her research landscape is strongly centered on atopic dermatitis, hidradenitis suppurativa, psoriasis, alopecia areata, bullous pemphigoid, prurigo nodularis, and vitiligo, reflecting broad involvement in inflammatory and autoimmune skin disorders.
- Atopic dermatitis
- Hidradenitis suppurativa
- Psoriasis
- Alopecia areata
- Bullous pemphigoid
Additional interest includes cutaneous lupus erythematosus and other chronic dermatologic conditions with immune dysregulation.
Cardiovascular Medicine and Thrombotic Risk
Investigator involvement spans acute coronary syndrome, myocardial infarction, ischemic stroke, atherosclerotic cardiovascular disease, arterial hypertension, heart failure with reduced ejection fraction, and broader prevention of cardiovascular events.
- Acute myocardial infarction
- Ischemic stroke prevention
- Atherosclerotic cardiovascular disease
- Hypertension
- Heart failure
Research also includes venous thrombosis and antithrombotic strategies for high-risk vascular disease.
Oncology and Advanced Solid Tumors
Her trial portfolio includes non-small cell lung cancer, melanoma, breast cancer, renal cell carcinoma, urothelial carcinoma, head and neck squamous cell carcinoma, and other advanced solid tumors.
- Non-small cell lung cancer
- Melanoma
- Breast cancer
- Renal cell carcinoma
- Urothelial carcinoma
There is also involvement in biomarker-defined malignancies, including KRAS G12C-mutant and EGFR-mutated disease.
Nephrology, Metabolic Disease, and Systemic Inflammation
Clinical interests extend to chronic kidney disease, non-diabetic chronic kidney disease, end-stage kidney disease, type 2 diabetes, obesity, and hyperlipidemia, alongside inflammatory conditions such as sepsis and community-acquired pneumonia.
- Chronic kidney disease
- Type 2 diabetes
- Obesity
- Sepsis
- Community-acquired pneumonia
Her portfolio also includes preeclampsia, retinopathy of prematurity, and other conditions involving systemic complications.
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