Davide-Paolo C.
- Country
- France
- Department
- Pulmonology, Department of Respiratory Diseases, Cystic Fibrosis Center Coordinator
Research Overview
- A Phase 3, Double-Blind, Placebo-Controlled, Randomized Study to Assess the Safety of Epicutaneous Immunotherapy with DBV712 250 µg in 1-through 3-year-old Children with Peanut Allergy
- A Multicentre, Randomised, Double-blind, Parallel Group, Placebocontrolled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients with Severe Eosinophilic Asthma (DOMINICA)
Data & Insights
Has run more than one trial at 2 of 36 partner sites.
Specializations
Pulmonary and airway disease
The investigator is active in clinical research on chronic obstructive pulmonary disease, severe asthma, eosinophilic asthma, bronchiectasis, cystic fibrosis, idiopathic pulmonary fibrosis, and interstitial lung disease, with additional involvement in pulmonary sarcoidosis, pulmonary hypertension, and chronic pulmonary aspergillosis.
- Asthma and eosinophilic airway inflammation
- COPD and chronic respiratory impairment
- Bronchiectasis and cystic fibrosis
- Pulmonary fibrosis and pulmonary hypertension
Research interests also extend to refractory chronic cough, respiratory failure, and other complex respiratory tract diseases.
Autoimmune and inflammatory disorders
Clinical activity includes studies in rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, lupus nephritis, systemic sclerosis, Sjögren’s syndrome, Crohn’s disease, and ulcerative colitis.
- Rheumatoid arthritis and psoriatic arthritis
- Systemic lupus erythematosus and lupus nephritis
- Systemic sclerosis and Sjögren’s syndrome
- Crohn’s disease and ulcerative colitis
Additional work spans vasculitis, dermatomyositis, mastocytosis, and other immune-mediated diseases.
Hematologic malignancies and transplantation
The investigator is involved in trials across acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, mantle cell lymphoma, follicular lymphoma, multiple myeloma, and other non-Hodgkin lymphomas.
- Acute leukemias and myelodysplastic syndromes
- B-cell and T-cell lymphomas
- Multiple myeloma and related plasma cell disorders
- Hematopoietic stem cell transplantation
Research also covers graft-versus-host disease, post-transplant lymphoproliferative disease, and cellular therapy in advanced blood cancers.
Cardiovascular and renal medicine
Clinical research interests include heart failure, atrial fibrillation, acute coronary syndrome, stroke, cardiogenic shock, atherosclerotic cardiovascular disease, and pulmonary arterial hypertension, alongside kidney-focused studies in chronic kidney disease, IgA nephropathy, and glomerular disease.
- Heart failure and cardiovascular disease
- Stroke and acute coronary syndromes
- Chronic kidney disease and IgA nephropathy
- Pulmonary arterial hypertension
Involvement also includes transplant-related renal complications and cardiometabolic risk.
Neurology, sleep, and rare disease
The investigator contributes to studies in multiple sclerosis, amyotrophic lateral sclerosis, Parkinson’s disease, Alzheimer’s disease, narcolepsy, idiopathic hypersomnia, and neurodevelopmental disorders, with additional activity in rare genetic diseases and sleep-wake disorders.
- Multiple sclerosis and neuroinflammatory disease
- Neurodegenerative disorders
- Sleep disorders
- Rare inherited diseases
Research also includes migraine, epilepsy, and other neurological disease areas.
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