David S. B.
- Country
- France
- Department
- Chirurgie viscérale
Research Overview
Data & Insights
Has run more than one trial at 0 of 16 partner sites.
Specializations
Gastrointestinal Oncology
The investigator concentrates on innovative therapies for malignancies of the digestive tract, emphasizing curative and palliative strategies.
- colorectal cancer
- gastric adenocarcinoma
- esophageal squamous cell carcinoma
- upper gastrointestinal tract malignancies
- colorectal liver metastasis
Research integrates surgical expertise with systemic treatment advances to improve survival across these entities.
Hepatobiliary and Pancreatic Diseases
Focus is placed on complex liver and pancreatic pathologies, targeting both malignant and benign conditions.
- hepatocellular carcinoma
- cholangiocarcinoma
- pancreatic ductal adenocarcinoma
- biliary tract cancer
- liver transplantation complications
Multidisciplinary protocols combine resection, ablative techniques, and novel systemic agents.
Metastatic Solid Tumor Management
Efforts are directed toward extending therapeutic options for patients with advanced, unresectable disease.
- metastatic colorectal cancer
- metastatic breast cancer
- metastatic renal cell carcinoma
- metastatic non‑small cell lung cancer
- multiorgan sarcoma metastasis
Clinical investigations explore combination regimens, biomarker‑guided selection, and maintenance approaches.
Rare and Aggressive Tumors
Special attention is given to low‑incidence neoplasms that lack established therapeutic standards.
- gastrointestinal stromal tumor
- neuroendocrine carcinoma
- primary hepatic sarcoma
- unresectable glioblastoma
- advanced melanomas with rare mutations
Investigations prioritize precision medicine and early‑phase therapeutic exploration.
Translational Immunotherapy & Targeted Therapies
Integration of immunologic and molecular insights drives the development of next‑generation treatments.
- HER2‑positive solid tumors
- PD‑L1‑expressing cancers
- FGFR‑altered malignancies
- KRAS‑mutant colorectal disease
- immune‑mediated amyloidosis
Collaborations with molecular pathology and immunology units enable rapid translation of biomarker‑driven strategies.
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