Dario M.
- Country
- Italy
- Department
- Nefrologia
Research Overview
Data & Insights
Has run more than one trial at 0 of 48 partner sites.
Specializations
Hematologic Malignancies
Investigator focuses on aggressive blood cancers, emphasizing targeted and immunotherapeutic strategies.
- FLT3‑mutated Acute Myeloid Leukemia
- Philadelphia chromosome‑positive Acute Lymphoblastic Leukemia
- Chronic Phase Chronic Myeloid Leukemia
- Early stage Follicular Lymphoma
- Relapsed or refractory Marginal Zone Lymphoma
Research includes evaluation of novel agents and combination regimens to improve remission durability.
Renal Immunology
Investigator advances therapeutic options for glomerular diseases, targeting proteinuria reduction.
- Idiopathic IgA Nephropathy
- Early corticosteroid therapy after kidney biopsy
- SGLT2 inhibitor combined with RAS blockers
- Corticosteroid‑based regimens versus standard care
Efforts aim to balance efficacy with safety by minimizing steroid‑related adverse effects.
Cardiovascular Intervention
Investigator explores acute coronary syndromes and microvascular protection to lower cardiac events.
- ST‑Elevation Myocardial Infarction with multivessel disease
- Late INa current inhibition for microvascular dysfunction
- Cardiovascular safety of novel agents in overweight patients
- Major adverse cardiovascular events (MACE) outcomes
Studies assess both procedural and pharmacologic strategies to preserve coronary function.
Metabolic and Obesity Therapy
Investigator addresses glycemic control and weight management through emerging pharmacotherapies.
- Type 2 Diabetes Mellitus with individualized HbA1c targets
- Obesity and overweight interventions
- Semaglutide as adjunct to reduced‑dose insulin
- Tirzepatide for morbidity and mortality reduction
- SGLT2 inhibitors to stabilize coronary atherosclerosis post‑MI
Research emphasizes cardiovascular risk mitigation alongside metabolic improvement.
Infectious Disease and Pandemic Response
Investigator contributes to therapeutic evaluation for viral respiratory illnesses, focusing on high‑risk populations.
- SARS‑CoV‑2 infection in hospitalized patients
- Baricitinib added to standard of care for immunocompromised hosts
- Outcome measures of disease progression and mortality
- Adaptive platform trial designs for emerging infections
Efforts target reduction of severe outcomes through targeted antiviral and anti‑inflammatory agents.
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