Danny H.
- Country
- Belgium
- Department
- Anesthesiology
Research Overview
Data & Insights
Has run more than one trial at 0 of 2 partner sites.
Specializations
Peri‑operative Oncology Anesthesia
The investigator concentrates on anesthetic strategies for patients undergoing surgery for advanced solid tumours, including breast cancer, non‑small cell lung cancer, and colorectal carcinoma.
- Optimisation of intra‑operative analgesia for metastatic breast disease
- Ventilatory management in lung resection for NSCLC
- Hemodynamic control during cytoreductive procedures for ovarian carcinoma
- Enhanced recovery pathways for gastrointestinal malignancies
These activities support safe surgical outcomes while addressing tumour‑related physiological challenges.
Critical Respiratory Medicine
Research targets severe pulmonary conditions such as nontuberculous mycobacterial lung infection, chronic obstructive pulmonary disease, and complex bronchiectasis.
- Airway protection strategies in patients with MAC infection
- Ventilation modes for severe COPD exacerbations
- Management of chronic pseudomonas colonisation in bronchiectasis
- Respiratory support for post‑lung‑transplant bronchiolitis obliterans
Focus lies on improving gas exchange and reducing ventilator‑associated complications.
Acute and Chronic Pain Management
Expertise includes multimodal analgesia for both surgical and disease‑related pain, spanning acute postoperative pain to persistent neuropathic syndromes.
- Opioid‑sparing regimens for major abdominal surgery
- Neuromodulatory techniques for chronic cancer‑related pain
- Assessment of analgesic efficacy in acute ischemic stroke
- Tailored pain protocols for patients with sickle cell vaso‑occlusive crises
Efforts aim to enhance patient comfort while minimising adverse drug effects.
Renal Transplant Immunology
The investigator studies immune mechanisms underlying kidney transplant rejection and antibody‑mediated processes, integrating peri‑operative care with long‑term graft preservation.
- Biomarker‑guided immunosuppression for acute antibody‑mediated rejection
- Peri‑operative fluid management in high‑risk renal recipients
- Evaluation of novel agents to prevent chronic allograft nephropathy
- Strategies to reduce delayed graft function after transplantation
These projects seek to improve graft survival and patient outcomes.
Neuro‑muscular and Autoimmune Disorders
Clinical interests extend to diseases such as generalised myasthenia gravis, systemic lupus erythematosus, and neurodegenerative conditions including amyotrophic lateral sclerosis.
- Peri‑operative ventilation strategies for myasthenic crisis
- Renal safety of immunomodulators in lupus nephritis
- Respiratory monitoring in ALS patients undergoing surgery
- Management of autoimmune neuropathies in the intensive care setting
Work emphasizes tailored anesthetic approaches that respect disease‑specific physiologic vulnerabilities.
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