Dainis K.
- Country
- Latvia
- Department
- N/A
Research Overview
- A Phase 2, Multicenter, Randomized, Open-Label, Active-Control Study of REGN9933, a Factor XI Monoclonal Antibody, for Prevention of Venous Thromboembolism after Elective, Unilateral, Total Knee Arthroplasty
- Evaluation of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients with Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease, and Systemic Inflammation
Data & Insights
Has run more than one trial at 6 of 244 partner sites.
Specializations
Cardiovascular & Thrombotic Medicine
The investigator concentrates on diseases of the heart and vessels, including acute coronary syndrome, myocardial infarction, atrial fibrillation, and systemic thromboembolic disorders.
- Acute coronary syndrome
- Atrial fibrillation
- Hypercholesterolemia
- Venous thromboembolism
- Heart failure with preserved ejection fraction
Research aims at reducing major adverse cardiovascular events and improving long‑term cardiac outcomes.
Pulmonary & Respiratory Therapeutics
Focus areas include chronic airway diseases such as asthma, chronic obstructive pulmonary disease, and rare conditions like bronchiectasis, as well as vascular lung disorders like pulmonary arterial hypertension.
- Asthma
- Chronic obstructive pulmonary disease
- Bronchiectasis
- Pulmonary arterial hypertension
- Interstitial lung disease‑associated pulmonary hypertension
Efforts target exacerbation reduction, functional capacity, and disease progression mitigation.
Oncology & Hematologic Malignancies
Clinical work spans solid tumors and blood‑related cancers, covering non‑small cell lung cancer, metastatic prostate cancer, bladder cancer, and hematologic conditions such as haemophilia A.
- Non‑small cell lung cancer
- Metastatic prostate cancer
- Muscle‑invasive bladder cancer
- Glioblastoma
- Haemophilia A
Investigations emphasize targeted therapies, disease‑free survival, and biomarker‑driven treatment strategies.
Neurology & Neurodegenerative Research
Key interests involve central nervous system disorders such as multiple sclerosis, amyotrophic lateral sclerosis, and seizure disorders like focal‑onset seizures, as well as cerebrovascular events.
- Multiple sclerosis
- Amyotrophic lateral sclerosis
- Focal‑onset seizures
- Acute ischemic stroke
- Neuroinflammatory demyelinating polyneuropathy
Research prioritizes disease modification, relapse prevention, and functional recovery.
Ophthalmology & Vision Science
Investigations address retinal and macular diseases, including diabetic macular edema, neovascular age‑related macular degeneration, and geographic atrophy.
- Diabetic macular edema
- Neovascular age‑related macular degeneration
- Geographic atrophy
- Macular edema secondary to retinal vein occlusion
- Retinal vascular diseases
Efforts focus on visual acuity preservation and slowing of disease progression.
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