Cyril F.
- Country
- France
- Department
- Oncology
Research Overview
- Evaluation of Ribociclib Combined with Endocrine Therapy in Hormone Receptor-Positive, HER2-Negative Early Breast Cancer: A Phase III Randomized Trial
- Evaluation of Palbociclib Combined with Endocrine Therapy in ER+/HER2- Metastatic Breast Cancer Using Circulating DNA ESR1 Mutation Monitoring
- Efficacy and Safety of Atezolizumab Versus Best Supportive Care Post-Adjuvant Cisplatin-Based Chemotherapy in Resected Stage IB-IIIA Non-Small Cell Lung Cancer
Data & Insights
Has run more than one trial at 61 of 295 partner sites.
Specializations
Thoracic oncology
Clinical research in non-small cell lung cancer includes immunotherapy-based strategies, perioperative treatment approaches, and maintenance treatment concepts, with interest in improving disease control across locally advanced and metastatic settings. The portfolio also extends to head and neck cancer and other squamous malignancies.
- Non-small cell lung cancer
- Head and neck cancer
- Cutaneous squamous cell carcinoma
- Anal squamous cell carcinoma
Therapeutic interest centers on checkpoint inhibitors, combined modality treatment, and adjuvant or neoadjuvant oncologic strategies.
Hepatobiliary and gastrointestinal oncology
Research activity covers hepatocellular carcinoma, biliary tract cancer, gastric cancer, colorectal cancer, and small bowel adenocarcinoma, with attention to advanced disease, liver-limited disease, and biomarker-driven treatment selection. The investigator is also involved in studies relevant to pancreatic adenocarcinoma and rectal cancer.
- Hepatocellular carcinoma
- Advanced biliary tract cancer
- Colorectal cancer
- Gastric and gastroesophageal junction adenocarcinoma
Therapeutic focus includes immunotherapy, anti-angiogenic treatment, perioperative oncology, and strategies for unresectable or high-risk disease.
Inflammatory and autoimmune diseases
The investigator is active in studies of giant cell arteritis, rheumatoid arthritis, primary Sjögren’s disease, granulomatosis with polyangiitis, and microscopic polyangiitis. Additional interest includes psoriasis, hidradenitis suppurativa, atopic dermatitis, and erosive osteoarthritis.
- Giant cell arteritis
- Rheumatoid arthritis
- Primary Sjögren’s disease
- Psoriatic and neutrophilic skin disease
Therapeutic domains include biologic therapy, JAK inhibition, and corticosteroid-sparing treatment.
Respiratory infection and chronic pulmonary disease
Clinical work includes nontuberculous mycobacterial lung infection, Mycobacterium xenopi pulmonary infection, chronic pulmonary aspergillosis, bronchiectasis, and chronic obstructive pulmonary disease. The investigator also engages with respiratory symptom outcomes in chronic airway infection.
- Nontuberculous mycobacterial lung infection
- Mycobacterium xenopi pulmonary infection
- Chronic pulmonary aspergillosis
- Bronchiectasis
Therapeutic interest is centered on antimicrobial regimens, inhaled treatment approaches, and management of persistent pulmonary infection.
Cardiometabolic and perioperative medicine
Research spans atherosclerotic cardiovascular disease, elevated lipoprotein(a), hypertension, type 2 diabetes, cardiac arrhythmia, and perioperative complications in cardiac surgery and colorectal surgery. The investigator also participates in studies related to metabolic dysfunction-associated steatohepatitis and primary sclerosing cholangitis.
- Atherosclerotic cardiovascular disease
- Elevated lipoprotein(a)
- Cardiac arrhythmia and postoperative atrial fibrillation
- Metabolic liver disease
Therapeutic focus includes lipid-lowering therapy, cardiovascular risk reduction, and perioperative prevention strategies.
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