Cristina P. I.
- Country
- Spain
- Department
- Hematology
Research Overview
- Evaluation of Iadademstat in the Management of Sickle Cell Disease in Affected Patients
- Safety and Preliminary Efficacy of CTX112 in Adults with Relapsed or Refractory Hematologic Autoimmune Disease
- Phase 3 Trial of VMX-C001 Versus Usual Care in Patients on Factor Xa DOACs Requiring Urgent High-Bleeding-Risk Surgery or Invasive Procedures
Data & Insights
Has run more than one trial at 74 of 198 partner sites.
Specializations
Hematologic Malignancies
Clinical research in Hematology with a strong focus on acute myeloid leukemia, myelodysplastic syndromes, multiple myeloma, and aggressive lymphomas, including diffuse large B-cell lymphoma, mantle cell lymphoma, and chronic lymphocytic leukemia.
- Acute leukemia
- Myelodysplastic syndromes
- Multiple myeloma
- Large B-cell lymphoma
- Chronic lymphocytic leukemia
Interest also extends to hematopoietic stem cell transplantation, graft-versus-host disease, immune thrombocytopenia, and other blood and lymphatic diseases.
Solid Tumors and Precision Oncology
Research activity covers a broad range of solid tumors, with emphasis on breast cancer, non-small cell lung cancer, colorectal cancer, pancreatic ductal adenocarcinoma, and gastrointestinal cancers.
- Breast cancer
- Non-small cell lung cancer
- Colorectal cancer
- Pancreatic cancer
- Gastroesophageal cancer
Therapeutic interests include targeted therapy, immunotherapy, and biomarker-driven care in melanoma, renal cell carcinoma, urothelial carcinoma, and prostate cancer.
Autoimmune and Inflammatory Disorders
Clinical trial involvement includes systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, psoriatic arthritis, systemic sclerosis, and idiopathic inflammatory myopathies.
- Systemic lupus erythematosus
- Lupus nephritis
- Rheumatoid arthritis
- Psoriatic arthritis
- Systemic sclerosis
Additional interest is evident in atopic dermatitis, hidradenitis suppurativa, Crohn's disease, ulcerative colitis, and other immune-mediated diseases.
Liver and Gastrointestinal Disease
Work in hepatology includes hepatocellular carcinoma, biliary tract cancer, cholangiocarcinoma, primary biliary cholangitis, primary sclerosing cholangitis, and metabolic dysfunction-associated steatohepatitis.
- Hepatocellular carcinoma
- Biliary tract cancer
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Metabolic dysfunction-associated steatohepatitis
Research also spans inflammatory bowel disease, chronic liver disease, cirrhosis, and cholestatic pruritus.
Cardiometabolic, Respiratory, and Rare Diseases
Additional clinical interests include heart failure, atherosclerotic cardiovascular disease, obesity, type 2 diabetes, chronic kidney disease, and pulmonary arterial hypertension.
- Heart failure
- Atherosclerotic cardiovascular disease
- Obesity
- Chronic kidney disease
- Pulmonary arterial hypertension
Activity also includes chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, multiple sclerosis, hereditary angioedema, and Fabry disease.
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