Cristina D. G.
- Country
- Spain
- Department
- Neurology
Research Overview
- Efficacy and Safety of DYNE-101 in Participants with Myotonic Dystrophy Type 1: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety Evaluation of Doxecitine and Doxribtimine in Adults with Thymidine Kinase 2 Deficiency: An Off-Label Single Arm Study
- A phase 2, multicenter, randomized, placebo-controlled, double-blind study to investigate the safety, pharmacodynamics, and preliminary efficacy of S-606001 as an add-on to enzyme replacement therapy in patients with late-onset Pompe disease.
Data & Insights
Has run more than one trial at 5 of 31 partner sites.
Specializations
Neurological Disorders
Cristina Dominguez Gonzalez is involved in clinical research across a broad neurological disease spectrum, with attention to disorders that affect cognition, movement, and seizure control. Her activity includes studies in Alzheimer’s disease, Parkinson’s disease, epilepsy, and other neurodegenerative conditions relevant to adult neurology.
- Alzheimer’s disease
- Parkinson’s disease
- Epilepsy
- Progressive supranuclear palsy
Her research landscape also reflects interest in cognitive impairment and movement disorders, supporting therapeutic development in chronic brain disease.
Neuro-Oncology and Solid Tumors
Her clinical trial portfolio includes extensive involvement in oncology, especially solid tumors with neurological relevance such as glioblastoma and brain metastases. The research scope extends to advanced cancers where tumor control and symptom burden are central therapeutic priorities.
- Glioblastoma
- Brain metastases
- Advanced solid tumors
- Head and neck cancer
She is also linked to studies in lung cancer, breast cancer, and other advanced malignancies, contributing to evolving treatment options in difficult-to-treat cancers.
Hematologic Malignancies
A major part of her research activity is centered on blood cancers, including lymphoma, leukemia, and multiple myeloma. This includes work in relapsed, refractory, and newly diagnosed hematologic disease settings where novel therapies are needed.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Acute myeloid leukemia
- Multiple myeloma
Her involvement also includes myelodysplastic syndromes and myelofibrosis, reflecting a therapeutic focus on malignancies of the bone marrow and lymphatic system.
Genitourinary and Gynecologic Cancers
Her clinical research includes strong engagement in genitourinary oncology and gynecologic cancer, particularly urothelial carcinoma, renal cell carcinoma, prostate cancer, ovarian cancer, and endometrial cancer. These areas reflect interest in both localized and metastatic disease.
- Urothelial carcinoma
- Renal cell carcinoma
- Prostate cancer
- Ovarian cancer
She is also involved in studies addressing cervical cancer and other advanced pelvic malignancies, supporting innovation in tumor-specific treatment strategies.
Immune-Mediated and Inflammatory Diseases
Her research interests extend into immune-mediated disease, including psoriatic arthritis, ulcerative colitis, Crohn’s disease, lupus, and atopic dermatitis. This indicates involvement in therapeutic areas where immune modulation is central to disease control.
- Psoriatic arthritis
- Ulcerative colitis
- Crohn’s disease
- Systemic lupus erythematosus
Her portfolio also touches on asthma, psoriasis, and other chronic inflammatory conditions, broadening the therapeutic reach of her clinical work.
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