Crisanda V.
- Country
- Romania
- Department
- Neurology
Research Overview
Data & Insights
Has run more than one trial at 0 of 54 partner sites.
Specializations
Neuroimmunology and Autoimmune Neurological Disorders
Research emphasizes disorders where immune mechanisms affect the nervous system, including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, myasthenia gravis, neurogenic detrusor overactivity and refractory epilepsy.
- Novel biologics for multiple sclerosis
- Targeted therapies for chronic inflammatory demyelinating polyneuropathy
- Immune modulation in myasthenia gravis
- Bladder dysfunction management in neurogenic detrusor overactivity
- Adjunctive treatments for refractory epilepsy
Clinical trials conducted at Institutul Clinic Fundeni integrate multidisciplinary approaches to advance care for these neurologic conditions.
Hematologic Malignancies and Cellular Therapies
Focus on blood‑borne cancers and innovative cellular products, such as acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, follicular lymphoma and CAR‑T cell therapy.
- Efficacy of novel agents in acute myeloid leukemia
- Maintenance strategies for chronic lymphocytic leukemia
- Combination regimens in multiple myeloma
- Targeted approaches for follicular lymphoma
- Safety profiling of CAR‑T cell therapy
Investigations aim to improve survival outcomes for patients with high‑risk hematologic diseases.
Hepatic and Metabolic Liver Disorders
Investigations address liver pathology ranging from viral hepatitis to metabolic steatohepatitis, covering non‑alcoholic steatohepatitis, hepatocellular carcinoma, chronic hepatitis C, primary biliary cholangitis and fibrosis progression.
- Therapeutic impact on non‑alcoholic steatohepatitis
- Targeted agents for hepatocellular carcinoma
- Antiviral strategies for chronic hepatitis C
- Disease‑modifying treatments for primary biliary cholangitis
- Biomarker‑driven monitoring of fibrosis progression
Trials conducted at the Bucharest site evaluate both disease‑specific and broad‑spectrum liver interventions.
Cardiovascular and Renal Risk Management
Research explores therapeutic options for heart disease and kidney dysfunction, especially in high‑risk populations, including atrial fibrillation, atherosclerotic cardiovascular disease, chronic kidney disease, hyperkalaemia and hypertension.
- Anticoagulant alternatives for atrial fibrillation
- Primary prevention of atherosclerotic cardiovascular disease
- Renal protective strategies in chronic kidney disease
- Management of hyperkalaemia in dialysis patients
- Blood pressure control in hypertension
The investigator collaborates with cardiology and nephrology teams to address comorbid disease burdens.
Gastrointestinal and Inflammatory Bowel Disease
Efforts target chronic intestinal inflammation and related gastrointestinal malignancies, focusing on crohn's disease, ulcerative colitis, colorectal cancer, gastroesophageal junction adenocarcinoma and chemotherapy‑induced nausea.
- Biologic induction for crohn's disease
- Maintenance therapies in ulcerative colitis
- Adjuvant strategies for colorectal cancer
- Targeted treatment of gastroesophageal junction adenocarcinoma
- Supportive care for chemotherapy‑induced nausea
Clinical programs integrate endoscopic and patient‑reported outcomes to refine therapeutic algorithms.
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