Corinne A. A.
- Country
- France
- Department
- Hématologie, oncologie et immunologie pédiatrique
Research Overview
- International cooperative prospective study for children and adolescents with standard risk ALK-positive anaplastic large cell lymphoma (ALCL) estimating the efficacy of Vinblastine
- Interfant-21: International collaborative treatment protocol for infants under one year with KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia
- International Pediatric Study of Arsenic Trioxide and Tretinoin ± Gemtuzumab Ozogamicin for Acute Promyelocytic Leukemia in Children and Adolescents
Data & Insights
Has run more than one trial at 112 of 237 partner sites.
Specializations
Pediatric Hematologic Malignancies
Focused on blood‑cancer entities that predominantly affect children and adolescents.
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Acute Promyelocytic Leukemia
- Hematopoietic Stem Cell Transplantation
- Graft‑Versus‑Host Disease
Clinical research emphasizes risk‑adapted therapy and post‑transplant immune monitoring.
Immuno‑hematology and Transplant Immunology
Investigations into immune‑mediated blood disorders and allo‑immune complications.
- ANCA‑Associated Vasculitis
- Immune Thrombocytopenia
- Autoimmune Hemolytic Anemia
- Antibody‑Mediated Rejection
- Allo‑immune Thrombotic Microangiopathy
Efforts target mechanistic insight and novel immunomodulatory strategies.
Solid Tumor Oncology (Targeted & Immunotherapy)
Therapeutic exploration of molecularly defined solid cancers.
- Advanced Non‑Small Cell Lung Cancer
- Metastatic Melanoma
- Hepatocellular Carcinoma
- Renal Cell Carcinoma
- Triple‑Negative Breast Cancer
Trials assess checkpoint inhibition, kinase‑targeted agents, and combination regimens.
Cardiovascular and Metabolic Disorders
Research addressing atherosclerotic disease and metabolic risk factors.
- Atherosclerotic Cardiovascular Disease
- Acute Coronary Syndrome
- Myocardial Infarction
- Obesity‑Related Sleep Apnea
- Chronic Kidney Disease with High Proteinuria
Investigations aim to reduce cardiovascular events through novel anti‑inflammatory approaches.
Pulmonary and Respiratory Immunology
Studies centered on inflammatory lung diseases and related immune pathways.
- Severe Asthma with Eosinophilic Phenotype
- Chronic Obstructive Pulmonary Disease
- Idiopathic Pulmonary Fibrosis
- Interstitial Lung Disease associated with Systemic Sclerosis
- Bronchiectasis
Efforts focus on biologic modulation of airway inflammation and fibrotic progression.
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