Corina Mihaela N.
- Country
- Romania
- Department
- Psychiatry
Research Overview
- Long-term Safety and Tolerability Evaluation of Trospium Chloride and Xanomeline Tartrate in Agitation Associated with Alzheimer's Disease
- Evaluation of the Safety and Efficacy of Trospium Chloride and Xanomeline Tartrate in Treating Agitation in Alzheimer's Disease: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for the Treatment of Cognitive Impairment Associated with Mild to Moderate Alzheimer’s Disease (MINDSET 1)
Data & Insights
Has run more than one trial at 48 of 109 partner sites.
Specializations
Schizophrenia and psychotic disorders
Clinical research activity includes treatments for acute schizophrenia, persistent psychotic symptoms, and schizophrenia-related cognitive and behavioral impairment, with a strong focus on symptom control in adult and adolescent populations.
- Acute schizophrenia
- Psychosis-associated symptoms
- Cognitive impairment in schizophrenia
- Adolescent schizophrenia
Areas of interest also extend to adjunctive approaches for negative symptoms and behavioral stabilization in people with inadequate response to antipsychotic treatment.
Bipolar I disorder and mania
The investigator is involved in therapeutic development for bipolar I disorder, with emphasis on acute manic episodes and manic states with mixed features.
- Acute mania
- Mania with mixed features
- Adjunctive mood stabilization
This work reflects a focus on improving control of severe mood elevation and related psychiatric instability.
Alzheimer’s disease and behavioral symptoms
Research interests include psychosis, hallucinations, delusions, and agitation associated with Alzheimer’s disease and Alzheimer’s dementia, alongside studies addressing cognitive and global functional decline.
- Agitation in Alzheimer’s dementia
- Psychosis in Alzheimer’s disease
- Hallucinations and delusions
- Cognitive impairment
The therapeutic landscape also includes interventions aimed at neuropsychiatric symptoms in mild to moderate disease.
Multiple sclerosis and pediatric neurology
Clinical activity covers relapsing-remitting multiple sclerosis, including pediatric disease, with interest in long-term disease control and relapse prevention.
- Pediatric multiple sclerosis
- Relapsing-remitting multiple sclerosis
- Relapse reduction
Additional neurological involvement includes seizure disorders such as childhood absence epilepsy, juvenile absence epilepsy, and Lennox-Gastaut syndrome.
Depression, migraine, and Tourette’s disorder
Further research spans major depressive disorder, including anhedonic and insomnia-associated presentations, as well as adolescent suicidal depression, pediatric migraine, and tic disorders.
- Major depressive disorder
- Pediatric migraine
- Tourette’s disorder
These interests show engagement across mood, pain, and neurodevelopmental therapeutic domains.
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