Clio P. M.
- Country
- Greece
- Department
- Department of Physiology
Research Overview
- Phase 2 Randomized, Double‑Blind, Placebo‑Controlled, Dose‑Ranging Study of Subcutaneous Nemolizumab in Adults with Systemic Sclerosis Assessing Skin Thickness
- Efficacy and Safety Evaluation of Subcutaneous Sibeprenlimab in Sjögren’s Disease: A Phase 2 Randomized, Double-blind, Placebo-controlled Trial
Data & Insights
Has run more than one trial at 3 of 66 partner sites.
Specializations
Autoimmune Rheumatic Diseases
Clinical research activity includes systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, systemic sclerosis, and antiphospholipid syndrome, with a strong emphasis on immune-mediated inflammation and connective tissue disease management.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Sjögren’s syndrome
- Systemic sclerosis
- Antiphospholipid syndrome
Work in this area also extends to cutaneous lupus erythematosus, idiopathic inflammatory myopathy, and other systemic autoimmune disorders seen in rheumatology practice.
Inflammatory Bowel and Gastrointestinal Disease
Research interests cover chronic inflammatory gastrointestinal conditions, especially Crohn’s disease, ulcerative colitis, pouchitis, and related immune-driven bowel disorders.
- Crohn’s disease
- Ulcerative colitis
- Chronic pouchitis
- Fistulizing perianal Crohn’s disease
- Coeliac disease
Therapeutic focus also includes broader immune-mediated gastrointestinal inflammation and refractory disease states requiring advanced anti-inflammatory strategies.
Cardiovascular and Thromboembolic Medicine
Clinical trial involvement spans atherosclerotic cardiovascular disease, heart failure, atrial fibrillation, hypertension, and stroke prevention, reflecting interest in cardiometabolic risk reduction and vascular protection.
- Atherosclerotic cardiovascular disease
- Heart failure
- Atrial fibrillation
- Ischemic stroke prevention
- Resistant hypertension
Additional activity includes myocardial infarction, systemic inflammation in cardiovascular disease, and prevention of major adverse cardiovascular events.
Respiratory and Infectious Diseases
Research engagement includes asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, non-tuberculous mycobacterial lung infection, and severe respiratory infections.
- Asthma
- Chronic obstructive pulmonary disease
- Idiopathic pulmonary fibrosis
- Severe viral lung infections
- COVID-19
The infectious disease portfolio also includes sepsis, candidemia, invasive candidiasis, and other serious hospital-acquired or opportunistic infections.
Hematologic Malignancies and Immune-Related Blood Disorders
Clinical research interests extend to lymphoma, acute myeloid leukemia, chronic lymphocytic leukemia, myelofibrosis, and myelodysplastic syndromes, alongside immune and coagulation disorders.
- Diffuse large B-cell lymphoma
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Myelofibrosis
- Hemophilia
Related interests include immune thrombocytopenia, autoimmune hemolytic anemia, and thalassemia, linking hematology with immune dysregulation and supportive care.
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