Clémence P.
- Country
- France
- Department
- intensive care
Research Overview
Data & Insights
Has run more than one trial at 0 of 10 partner sites.
Specializations
Critical Care and Cardiovascular Therapeutics
The investigator concentrates on acute life‑support conditions encountered in the intensive care environment, including cardiovascular emergencies and severe respiratory failure.
- Out-of-hospital cardiac arrest
- Acute myocarditis
- Acute coronary syndrome
- Low-dose rivaroxaban for cardiovascular risk
- Cardiovascular outcomes in chronic kidney disease
Clinical focus includes rapid‑response pharmacologic strategies and outcome optimization in critically ill patients.
Renal and Hypertension Management
Research addresses progressive kidney injury and blood‑pressure dysregulation, targeting both early and end‑stage disease stages.
- Chronic kidney disease progression
- End‑stage renal disease
- High proteinuria
- Uncontrolled hypertension in CKD
- Zibotentan and dapagliflozin combination
Therapeutic goals are to decelerate renal decline and mitigate cardiovascular risk.
Hematologic Malignancies and Immunotherapy
The portfolio spans malignant hematopoietic disorders, emphasizing novel immunologic and molecular interventions.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Chronic lymphocytic leukemia
- Peripheral T‑cell lymphoma
- Multiple myeloma
- Bispecific antibodies in lymphoma
Efforts aim to improve remission durability and reduce treatment‑related toxicity.
Solid Tumor Oncology and Targeted Therapies
Investigations target diverse solid tumors, with a strong emphasis on molecularly defined subtypes and combination immunotherapy.
- Non‑small cell lung cancer
- Small cell lung cancer
- Advanced ROS1‑positive lung cancer
- BRAF‑mutant lung cancer
- HER2‑mutant lung cancer
- Hepatocellular carcinoma
- Renal cell carcinoma
- Metastatic colorectal cancer
Personalized treatment strategies are pursued through biomarker‑driven clinical evaluation.
Autoimmune and Systemic Immune‑Mediated Disorders
Work includes systemic autoimmune conditions characterized by organ‑specific immune injury.
- ANCA vasculitis
- Sjögren’s syndrome
- Systemic lupus erythematosus
- IgA nephropathy
- Autoimmune glomerular diseases
- Prurigo nodularis
Therapeutic development seeks to modulate pathogenic pathways while preserving organ function.
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