Claudio G.
- Country
- Italy
- Department
- Dpt. Testa Collo, UOC Neurologia e Neurofisiopatologia
Research Overview
- A Phase 3 Non-inferiority Study Comparing Subcutaneous versus Intravenous Administration of Frexalimab in Adults with Multiple Sclerosis
- Phase 3 Extension Study on Long-term Safety and Tolerability of Tolebrutinib in Relapsing and Progressive Multiple Sclerosis
- Evaluation of Safety and Efficacy of CLS12311 in Patients with Relapsing Remitting Multiple Sclerosis: A Phase Ib/IIa Multicenter Study
Data & Insights
Has run more than one trial at 98 of 233 partner sites.
Specializations
Neurovascular and Thromboembolic Disorders
Clinical research activity includes acute ischemic stroke, high-risk transient ischemic attack, intracerebral haemorrhage, atrial fibrillation, and broader cardiovascular disease prevention, with interest in reducing ischemic risk and improving outcomes after cerebrovascular events.
- Stroke prevention and acute management
- Atrial fibrillation and embolic risk reduction
- Heart failure and ischemic cardiovascular events
Work in this area connects neurological care with cardiovascular protection and secondary prevention strategies.
Multiple Sclerosis and Autoimmune Neurology
Research involvement extends to multiple sclerosis, relapsing-remitting multiple sclerosis, and radiologically isolated syndrome, reflecting a focus on inflammatory demyelinating disease and long-term disease control.
- Relapsing multiple sclerosis
- Progressive multiple sclerosis
- Nervous system diseases with immune-mediated features
Therapeutic interest also covers sustained control of neurologic autoimmunity and treatment options for chronic disease activity.
Inflammatory Bowel Disease and Immune-Mediated Gastroenterology
Clinical trial participation includes Crohn's disease, ulcerative colitis, and overlapping immune system diseases, with emphasis on intestinal inflammation and maintenance of disease control.
- Moderately to severely active Crohn's disease
- Moderately to severely active ulcerative colitis
- Intestinal malabsorption and inflammatory complications
The therapeutic landscape includes biologic and targeted approaches for chronic gastrointestinal immune disorders.
Systemic Autoimmune and Renal Disease
Research interests include systemic lupus erythematosus, lupus nephritis, and immunoglobulin A nephropathy, alongside related inflammatory renal and systemic immune conditions.
- Systemic lupus erythematosus
- Lupus nephritis
- Immunoglobulin A nephropathy
This area reflects involvement in therapies aimed at controlling systemic autoimmunity and protecting renal function.
Oncology and Hematologic Malignancies
Clinical research activity spans non-small cell lung cancer, colorectal cancer, cholangiocarcinoma, renal cell carcinoma, urothelial cancer, and hematologic malignancies including diffuse large B-cell lymphoma, Hodgkin's lymphoma, acute myeloid leukemia, and Philadelphia chromosome-positive acute lymphoblastic leukemia.
- Non-small cell lung cancer and molecularly selected thoracic tumors
- Colorectal, pancreatic, and gastroesophageal cancers
- Lymphoma, leukemia, and other blood cancers
The therapeutic scope includes targeted oncology, immunotherapy, and perioperative or advanced-disease treatment strategies across solid and hematologic tumors.
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