Claire M. J.
- Country
- France
- Department
- Hospitalisation à domicile
Research Overview
Data & Insights
Has run more than one trial at 0 of 1 partner site.
Specializations
Home‑Based Respiratory Care
The investigator focuses on the outpatient management of chronic pulmonary infections, particularly non‑tuberculous mycobacterial (NTM) lung disease and complex bronchiectasis cases requiring home hospitalization.
- NTM lung infection
- Bronchiectasis with Pseudomonas colonisation
- Chronic respiratory failure in home‑care settings
These efforts aim to reduce hospital readmissions and improve quality of life for patients with persistent respiratory pathology.
Hereditary Transthyretin Amyloidosis
She is actively engaged in therapeutic strategies for hereditary transthyretin amyloidosis manifesting as polyneuropathy or cardiomyopathy, addressing both neurological and cardiac sequelae.
- ATTRv‑PN (polyneuropathy)
- ATTR‑CM (cardiomyopathy)
- Genotype‑guided disease‑modifying treatment
Her work supports early diagnosis and targeted intervention to slow disease progression.
Systemic Autoimmune Disorders
The investigator’s portfolio includes a range of immune‑mediated diseases such as primary Sjögren’s syndrome, ANCA‑associated vasculitis, and systemic lupus erythematosus with renal involvement.
- Primary Sjögren’s syndrome
- ANCA‑associated vasculitis
- Active lupus nephritis
- Peripheral neuropathy of autoimmune origin
These initiatives prioritize organ‑preserving therapies and biomarker‑driven patient stratification.
Rare Head‑and‑Neck and Biliary Malignancies
She contributes to oncologic research on uncommon solid tumours, including resected and non‑operable salivary‑gland tumors and advanced biliary tract carcinoma, often within multidisciplinary home‑care pathways.
- Salivary‑gland carcinoma
- Advanced biliary tract carcinoma
- Unresectable sinonasal malignancies
- Targeted therapy for KRAS‑mutated colorectal cancer
Her focus is on integrating systemic treatments with supportive home‑based care to maintain functional status.
Acute Cardiovascular and Renal Syndromes
In the critical care arena, she investigates acute events such as acute coronary syndrome, acute kidney injury, and heart failure exacerbations, emphasizing rapid transition to home‑based monitoring when feasible.
- Acute myocardial infarction
- Acute kidney injury in intensive care
- Heart failure with preserved ejection fraction
- Post‑cardiac arrest syndrome management
These projects seek to streamline discharge planning and reduce rehospitalisation risk.
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