person

Claire M. J.

Country
France
Department
Hospitalisation à domicile

Research Overview

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
0
Sites with multiple studies

Has run more than one trial at 0 of 1 partner site.

Specializations

Home‑Based Respiratory Care

The investigator focuses on the outpatient management of chronic pulmonary infections, particularly non‑tuberculous mycobacterial (NTM) lung disease and complex bronchiectasis cases requiring home hospitalization.

  • NTM lung infection
  • Bronchiectasis with Pseudomonas colonisation
  • Chronic respiratory failure in home‑care settings

These efforts aim to reduce hospital readmissions and improve quality of life for patients with persistent respiratory pathology.

Hereditary Transthyretin Amyloidosis

She is actively engaged in therapeutic strategies for hereditary transthyretin amyloidosis manifesting as polyneuropathy or cardiomyopathy, addressing both neurological and cardiac sequelae.

  • ATTRv‑PN (polyneuropathy)
  • ATTR‑CM (cardiomyopathy)
  • Genotype‑guided disease‑modifying treatment

Her work supports early diagnosis and targeted intervention to slow disease progression.

Systemic Autoimmune Disorders

The investigator’s portfolio includes a range of immune‑mediated diseases such as primary Sjögren’s syndrome, ANCA‑associated vasculitis, and systemic lupus erythematosus with renal involvement.

  • Primary Sjögren’s syndrome
  • ANCA‑associated vasculitis
  • Active lupus nephritis
  • Peripheral neuropathy of autoimmune origin

These initiatives prioritize organ‑preserving therapies and biomarker‑driven patient stratification.

Rare Head‑and‑Neck and Biliary Malignancies

She contributes to oncologic research on uncommon solid tumours, including resected and non‑operable salivary‑gland tumors and advanced biliary tract carcinoma, often within multidisciplinary home‑care pathways.

  • Salivary‑gland carcinoma
  • Advanced biliary tract carcinoma
  • Unresectable sinonasal malignancies
  • Targeted therapy for KRAS‑mutated colorectal cancer

Her focus is on integrating systemic treatments with supportive home‑based care to maintain functional status.

Acute Cardiovascular and Renal Syndromes

In the critical care arena, she investigates acute events such as acute coronary syndrome, acute kidney injury, and heart failure exacerbations, emphasizing rapid transition to home‑based monitoring when feasible.

  • Acute myocardial infarction
  • Acute kidney injury in intensive care
  • Heart failure with preserved ejection fraction
  • Post‑cardiac arrest syndrome management

These projects seek to streamline discharge planning and reduce rehospitalisation risk.

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