Christine C.
- Country
- France
- Department
- Dermatology
Research Overview
- A double-blind, randomized, placebo-controlled, interventional, multicenter, phase III clinical trial to investigate the safety and efficacy of ABCB5-positive mesenchymal stromal cells (ABCB5+ MSCs) on epidermolysis bullosa (EB)
- A Phase II double-blind multi-center, placebo-controlled trial, to assess the efficacy and safety of alpelisib (BYL719) in pediatric and adult patients with Megalencephaly-CApillary malformation Polymicrogyria syndrome (MCAP)
- GENEPID: A 44-weeks monocentric open study assessing the efficacy and safety of Deucravacitinib in adults with Inflammatory EPidermal GENodermatoses (epidermolysis bullosa simplex and inflammatory congenital ichthyoses)
Data & Insights
Has run more than one trial at 4 of 36 partner sites.
Specializations
Rare Skin Disorders
The investigator specializes in the treatment of epidermolysis bullosa, with particular focus on its various subtypes including recessive dystrophic epidermolysis bullosa (RDEB), junctional epidermolysis bullosa (JEB), and epidermolysis bullosa simplex.
- Advanced Cell Therapies
- Genetic Skin Conditions
- Pediatric Dermatology
Clinical expertise extends to novel therapeutic approaches for managing severe skin fragility disorders.
Neurological Conditions
Research interests include the treatment of Megalencephaly-Capillary Malformation Polymicrogyria Syndrome (MCAP), focusing on innovative therapeutic interventions to improve adaptive behavior in both pediatric and adult patients.
- Developmental Disorders
- Neurovascular Conditions
- Targeted Therapies
Expertise in managing complex neurological manifestations and associated developmental challenges.
Inflammatory Skin Conditions
The investigator focuses on treating inflammatory epidermal genodermatoses, including erythrodermic congenital ichthyosis and keratinopathic ichthyosis.
- Congenital Ichthyosis
- Novel Therapeutic Approaches
- Long-term Disease Management
Specialized interest in developing treatment strategies for severe inherited skin disorders.
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