Chiara U.
- Country
- Italy
- Department
- UO Pediatria
Research Overview
Data & Insights
Has run more than one trial at 0 of 19 partner sites.
Specializations
Kidney Disease
Investigation of therapeutic strategies to slow renal function decline in patients with Autosomal Dominant Polycystic Kidney Disease.
- Renal function preservation
- eGFR trajectory
- Long‑term disease‑free outcome
Focus includes comparison of disease‑modifying agents in adult cohorts.
Lung Cancer
Evaluation of targeted treatment efficacy in individuals diagnosed with EGFR mutant non‑small cell lung cancer stratified by TP53 status.
- Progression‑free survival
- Molecular biomarker impact
- Personalized therapy selection
Research emphasizes genotype‑guided therapeutic decisions.
Colorectal Oncology
Study of adjuvant therapeutic outcomes for patients with high‑risk stage III colon cancer.
- Disease‑free survival
- Adjuvant chemotherapy optimization
- Risk‑adjusted treatment pathways
Efforts aim to refine postoperative management protocols.
Breast Cancer
Implementation of biomarker‑driven approaches for HR‑positive, HER2‑negative metastatic breast cancer.
- Second‑line treatment intensity
- Liquid biopsy integration
- Therapeutic personalization
Projects target improved outcomes through molecular monitoring.
Ovarian Cancer
Exploration of maintenance strategies in patients with recurrent ovarian cancer lacking germline or somatic BRCA alterations.
- Biomarker‑guided maintenance therapy
- Platinum‑sensitivity assessment
- Prognostic molecular profiling
Research focuses on extending remission periods without BRCA‑targeted agents.
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