Charlotte J.
- Country
- France
- Department
- Paediatric haematology oncology
Research Overview
- Phase 3 Study of Imatinib with Cytotoxic Chemotherapy in Pediatric Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
- Phase 2 Multicenter Trial of Mesenchymal Stromal Cells MC0518 vs. Best Available Therapy in Pediatric Steroid-Refractory Acute Graft-Versus-Host Disease
- Dose and Safety Evaluation of Asciminib in Pediatric Patients with Philadelphia Chromosome Positive Chronic Myeloid Leukemia in Chronic Phase
Data & Insights
Has run more than one trial at 114 of 189 partner sites.
Specializations
Leukemia Treatment
This investigator specializes in treating various forms of acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML) in pediatric patients. Their work encompasses both newly diagnosed cases and relapsed conditions, with particular attention to Philadelphia chromosome-positive variants.
- Philadelphia chromosome-positive chronic myeloid leukemia
- Acute lymphoblastic leukemia management
- High-risk relapsed ALL treatment
Their expertise extends to innovative therapeutic approaches using tyrosine kinase inhibitors and targeted therapies.
Stem Cell Transplantation
The investigator focuses on allogeneic stem cell transplantation procedures in young patients with leukemia. Their work involves various conditioning regimens and donor compatibility scenarios.
- HLA-matched donor transplantation
- Alternative donor strategies
- Conditioning protocol optimization
Special attention is given to transplantation outcomes in different age groups and donor types.
Transplant Complications
A significant focus is placed on managing post-transplant complications, particularly steroid-refractory acute graft-versus-host disease in pediatric patients.
- Graft-versus-host disease management
- Novel therapeutic approaches
- Treatment resistance strategies
The investigator explores innovative therapeutic options for transplant-related complications.
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