Charles F.
- Country
- France
- Department
- Service de Cardiologie
Research Overview
- Phase III Randomized Double‑Blind Trial of Elecoglipron (AZD5004) on Cardiovascular Mortality and Hospitalization in Adults with HFpEF or HFmrEF on Background Dapagliflozin
- Evaluation of Balcinrenone and Dapagliflozin on Cardiovascular Outcomes in Heart Failure Patients with Renal Impairment: A Phase III Randomized, Double-Blind Study
- Discontinuation of Beta-Blockers in Heart Failure Patients with Recovered Left Ventricular Ejection Fraction: A Non-Inferiority Study
Data & Insights
Has run more than one trial at 117 of 499 partner sites.
Specializations
Cardiovascular Disease Management
The investigator specializes in treating patients with heart failure, particularly focusing on novel therapeutic approaches for those with impaired kidney function. Their research encompasses the evaluation of combination therapies involving balcinrenone and dapagliflozin for cardiovascular outcomes.
- Heart Failure Treatment
- Cardiorenal Syndrome
- Cardiovascular Death Prevention
Their expertise extends to managing complex cases where heart failure coexists with renal complications.
Innovative Therapeutic Solutions
The investigator conducts research on emerging treatments for heart failure patients with reduced left ventricular ejection fraction. Their work includes evaluating novel compounds like XXB750 and their effects on cardiac biomarkers such as NT-proBNP.
- Biomarker Assessment
- Dose-Response Studies
- Standard of Care Optimization
Their research focuses on patients receiving contemporary heart failure therapies including ACE inhibitors and ARBs.
Treatment Optimization Studies
The investigator explores treatment optimization strategies, particularly in patients with recovered left ventricular ejection fraction. Their research evaluates the safety and efficacy of discontinuing beta-blocker therapy in specific patient populations.
- Beta-Blocker Management
- Heart Failure Recovery
- Cardiovascular Outcomes
Their work includes differentiated approaches for ischemic and non-ischemic heart failure etiologies.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.