Cesar V. E.
- Country
- Spain
- Department
- Haematology
Research Overview
Data & Insights
Has run more than one trial at 0 of 6 partner sites.
Specializations
Breast Cancer Therapeutics
Focuses on advanced and early‑stage hormone receptor‑positive, HER2‑negative, triple‑negative, HER2‑positive, HER2‑low tumors and those with BRCA alterations.
- PARP inhibition combined with endocrine therapy
- Antibody‑drug conjugates targeting HER2 pathways
- PI3K/AKT pathway modulation in resistant disease
- Combination immunotherapy for triple‑negative disease
Therapeutic strategies aim to improve progression‑free survival and achieve deeper pathological responses.
Neurodegenerative Disease Interventions
Targets early and mild stages of Alzheimer disease and Parkinson disease, addressing both tau pathology and amyloid accumulation.
- Anti‑tau monoclonal antibodies
- Amyloid‑targeted immunotherapies
- Cognitive decline mitigation agents
- Motor symptom modulators for early Parkinsonism
Research emphasizes disease‑modifying effects and functional preservation.
Ophthalmic Vascular and Degenerative Disorders
Investigates conditions such as diabetic retinopathy, diabetic macular edema, retinal vein occlusion and neovascular age‑related macular degeneration.
- Intravitreal anti‑VEGF agents
- Port delivery system for sustained ocular drug release
- Complement pathway inhibition for geographic atrophy
- Retinal fluid reduction and visual acuity preservation
Clinical goals include reducing lesion growth and improving visual outcomes.
Autoimmune Neuromuscular and Myasthenic Disorders
Addresses generalized myasthenia gravis and associated acetylcholine receptor antibodies, focusing on disease control and quality of life.
- Induction immunotherapy with monoclonal antibodies
- Maintenance strategies to sustain remission
- Functional activity scoring for treatment response
- Safety profiling of long‑term antibody use
Efforts aim to achieve rapid symptom relief and durable disease stabilization.
Infectious Disease Prevention and Pediatric Vaccination
Focuses on prophylaxis against respiratory syncytial virus and evaluation of meningococcal vaccine immunogenicity in infants and toddlers.
- Long‑acting monoclonal antibody for RSV prevention
- Multivalent conjugate vaccine formulations
- Serum bactericidal activity assessment
- Safety monitoring across pediatric age groups
Studies aim to protect vulnerable populations and establish robust immune responses.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.